According to the National Institute on Drug Abuse, "Fentanyl is a powerful synthetic opioid analgesic that is similar to morphine but is 50 to 100 times more potent. It is a schedule II prescription drug, and it is typically used to treat patients with severe pain or to manage pain after surgery. It is also sometimes used to treat patients with chronic pain who are physically tolerant to other opioids. In its prescription form, fentanyl is known by such names as Actiq®, Duragesic®, and Sublimaze®. Street names for fentanyl or for fentanyl-laced heroin include Apache, China Girl, China White, Dance Fever, Friend, Goodfella, Jackpot, Murder 8, TNT, and Tango and Cash."4
According to the National The National Institute on Drug Abuse, "NIDA-supported basic and clinical research led to the development of buprenorphine, a medication for the treatment of heroin addiction. These scientific discoveries spurred a collaboration with industry, which culminated in FDA approval of Subutex® (buprenorphine) and Suboxone® tablets (buprenorphine/ naloxone) in October 2002. Buprenorphine is a long-acting partial mu opiate agonist that acts on the receptor targets of heroin and morphine, but does not produce the same intense "high" or dangerous side effects. These properties also make it a good potential treatment for addiction to opiate analgesics."3
OxyContin® tablets are a controlled-release oral formulation of oxycodone hydrochloride generally indicated for the management of moderate to severe pain when a continuous, around-the-clock analgesic is needed for an extended period. Oxycodone is a semisynthetic narcotic analgesic classified by the US Drug Enforcement Administration as a Schedule II controlled substance with an abuse liability similar to morphine.
Labcorp offers a variety of options for opiate testing, including panels designed to detect one or more of the following: codeine, morphine, hydrocodone, hydromorphone, oxycodone, oxymorphone, methadone, buprenorphine, tramadol, meperidine and fentanyl. Your Labcorp sales representative can assist you in determining the best profile to meet your testing needs.
6-acetylmorphine (6-AM) is an intermediate metabolite between heroin and morphine. Generally, 6-AM is present for a short time after use of heroin. A finding of 6-AM in urine or oral fluid is a specific indication of heroin use or exposure; 6-AM has not been shown to be derived from any other source.
3. What Buprenorphine is and Why It's Important, accessed July 13, 2016. http://archives.drugabuse.gov/drugpages/buprenorphine.html
4. Fentanyl, accessed July 13, 2016. https://www.drugabuse.gov/drugs-abuse/fentanyl