Alert:
Labcorp has multiple COVID-19 testing options. Learn more >>>
Synonyms
- Anti-H pylori, IgG
- Anti-Helicobacter pylori Antibodies
Test Includes
Qualitative result for IgG
Expected Turnaround Time
1 - 3 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
Related Documents
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube, gel-barrier tube, or serum transfer tube
Storage Instructions
Maintain specimen at room temperature.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x4 |
Causes for Rejection
Non-serum samples; heat-inativated serum; grossly hemolyzed; icteric or lipemic; samples containing particulate matter or exhibiting obvious microbial contamination
Test Details
Use
The qualitative determination of IgG antibodies to Helicobacter pylori (H. pylori) in human serum from symptomatic adults as an aid in the diagnosis of H. pylori infection.
Limitations
Assay results should be utilized in conjunction with other clinical and laboratory data to assist the clinician in making individual patient management decisions. Heterophilic antibodies in human serum can react with reagent immunoglobulins or other reagent material, interfering with in vitro immunoassays.
This assay has not been evaluated in a pediatric population.
This assay should be used only to evaluate patients with clinical signs and symptoms suggestive of gastrointestinal disease and is not intended for use with asymptomatic patients.
A positive test result does not allow one to distinguish between active infection and colonization by H. pylori. A positive test only indicates the presence of IgG antibody to H. pylori and does not necessarily indicate that gastrointestinal disease is present.
A negative test indicates that IgG antibody to H. pylori is not present or is at a level that cannot be detected by the assay.
Methodology
Chemiluminescence immunoassay (CLIA)
Reference Interval
• Negative: <0.80
• Equivocal: 0.80 - 0.89
• Positive: >0.89
References
Amieva MR, El‐Omar EM. Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology. 2008 Jan;134(1):306-323.18166359
Brown LM. Helicobacter pylori: epidemiology and routes of transmission. Epidemiol Rev. 2000;22(2):283‐297.11218379
DiaSorin LIAISON®. H. pylori IgG [package insert]. (REF 318980), US-47667-2017-01.
Kusters JG, van Vliet AH, Kuipers EJ. Pathogensis of Helicobacter pylori infection. Clin Microbiol Rev. 2006 Jul;19(3):449-490.16847081
Megraud F. Transmission of Helicobacter pylori: faecal-oral versus oral-oral route. Aliment Pharmacol Ther. 1995;9 Suppl 2:85-91.8547533
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 162289 | H. pylori, IgG Abs | 5176-3 | 162314 | H. pylori, IgG Abs | Index Value | 5176-3 |
© 2021 Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.
CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf