Helicobacter pylori Antibodies, IgG

CPT: 86677
Print Share


  • Anti-H pylori, IgG
  • Anti-Helicobacter pylori Antibodies

Test Includes

Qualitative result for IgG

Expected Turnaround Time

1 - 3 days

Related Documents

Specimen Requirements




1 mL

Minimum Volume

0.5 mL (Note: This volume does not allow for repeat testing.)


Red-top tube, gel-barrier tube, or serum transfer tube

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x4

Causes for Rejection

Non-serum samples; heat-inativated serum; grossly hemolyzed; icteric or lipemic; samples containing particulate matter or exhibiting obvious microbial contamination

Test Details


The qualitative determination of IgG antibodies to Helicobacter pylori (H. pylori) in human serum from symptomatic adults as an aid in the diagnosis of H. pylori infection.


Assay results should be utilized in conjunction with other clinical and laboratory data to assist the clinician in making individual patient management decisions. Heterophilic antibodies in human serum can react with reagent immunoglobulins or other reagent material, interfering with in vitro immunoassays.

This assay has not been evaluated in a pediatric population.

This assay should be used only to evaluate patients with clinical signs and symptoms suggestive of gastrointestinal disease and is not intended for use with asymptomatic patients.

A positive test result does not allow one to distinguish between active infection and colonization by H. pylori. A positive test only indicates the presence of IgG antibody to H. pylori and does not necessarily indicate that gastrointestinal disease is present.

A negative test indicates that IgG antibody to H. pylori is not present or is at a level that cannot be detected by the assay.


Chemiluminescence immunoassay (CLIA)

Reference Interval

• Negative: <0.80

• Equivocal: 0.80 - 0.89

• Positive: >0.89


Amieva MR, El‐Omar EM. Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology. 2008 Jan;134(1):306-323.18166359
Brown LM. Helicobacter pylori: epidemiology and routes of transmission. Epidemiol Rev. 2000;22(2):283‐297.11218379
DiaSorin LIAISON®. H. pylori IgG [package insert]. (REF 318980), US-47667-2017-01.
Kusters JG, van Vliet AH, Kuipers EJ. Pathogensis of Helicobacter pylori infection. Clin Microbiol Rev. 2006 Jul;19(3):449-490.16847081
Megraud F. Transmission of Helicobacter pylori: faecal-oral versus oral-oral route. Aliment Pharmacol Ther. 1995;9 Suppl 2:85-91.8547533


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
162289 H. pylori, IgG Abs 5176-3 162314 H. pylori, IgG Abs Index Value 5176-3

For Providers

Please login to order a test

Order a Test

© 2021 Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf