CPT: 82735
Print Share

Expected Turnaround Time

3 - 4 days

Related Information

Specimen Requirements


Serum or plasma


3 mL

Minimum Volume

1.1 mL


Royal blue-top (EDTA) tube or royal blue-top without EDTA


Submit original unopened tube or serum or plasma removed from a royal blue-top tube.

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements



Room temperature

7 days


7 days


14 days

Freeze/thaw cycles

Stable x1

Test Details


Monitor exposure to fluoride


Ion-selective electrode (ISE) potentiometry

Reference Interval

Environmental exposure: <0.2 mg/L

Additional Information

Fluoride poisoning through chronic exposure to fluoride and its inorganic compounds is generally associated with industry. The effects of fluoride overexposure are generally manifested initially in mucous membrane irritation. Increased intensity of the exposure may produce respiratory distress, neurological abnormalities, gastrointestinal pain, and muscular fibrillation. Prolonged exposure over years can lead to skeletal fluorosis, a crippling disease. Acute exposure is more commonly the result of the ingestion of fluorides and is manifested by symptoms of nausea, vomiting, tetanic contractions, coma, and death.1 Fluoride and its inorganic compounds are widely employed in industry, including glass manufacture and in the aluminum, steel, and fertilizer industries. Fluoride compounds are also employed as insecticides, rodenticides, and delousing powders. In an organic state, fluoride is an essential mineral in man required for bone calcification processes. Overexposure is generally attributed to occupational causes, which are typically of a chronic nature. Acute exposure is more commonly the result of the ingestion of fluorides.


1. Baselt RC, Cravey RH. Disposition of Toxic Drugs and Chemicals in Man. 4th ed. Chemical Toxicology Institute;1995.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
070060 Fluoride, Serum 5649-9 070060 Fluoride, Serum mg/L 5649-9

For Providers

Please login to order a test

Order a Test

© 2021 Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf