Microarray-Tumor Reveal® FFPE

CPT: 81229
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Test Details


  • aCGH
  • CGH
  • CMA
  • Microarray Oncology
  • Reveal® SNP Array
  • WGA


High resolution detection of genomic imbalances that may be present in neoplastic clonal evolution; provides detection of copy-neutral loss of heterozygosity (acquired uniparental disomy) associated with cancer gene mutation. The microarray will detect DNA copy-number changes at a threshold >1 Mb for deletions, >2 Mb for duplications.


This assay does not detect balanced rearrangements and low level mosaicism, or tetraploidy.

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).


Whole genome SNP copy number microarray analysis using Molecular Inversion Probe (MIP) technology optimized for highly degraded FFPE samples or degraded fixed cell pellets.

Specimen Requirements


Formalin fixed paraffin embedded (FFPE) tissue; fixed cell pellets


One paraffin block or ten 10-micron thick section slides

Minimum Volume

Sufficient sample to obtain enough DNA to run microarray


Paraffin block transport pouch


FFPE specimen should be fixed in 10% neutral-buffered formalin or formaldehyde. Cell pellet should be fixed in 3:1 methanol:acetic acid.

Storage Instructions

Room temperature

Causes for Rejection

Improperly embedded preparation; decalcified bone or bone core

Clinical Information

Special Instructions

Pertinent medical findings should accompany the test request form. If prior FISH analysis has been performed, include copy of report. Please direct questions to genetic customer service at 800-345-4363.

This assay is not approved for patients of New York State physicians.


Nauen D, Haley L, Lin MT, et al. Molecular analysis of pediatric oligodendrogliomas highlights genetic differences with adult counterparts and other pediatric gliomas. Brain Pathol. 2016 Mar;26(2):206-214.26206478


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
512014 Reveal(R) Tumor Paraffin 511936 PDF 80563-0
512014 Reveal(R) Tumor Paraffin 512005 Reveal(R) Tumor Paraffin N/A
512014 Reveal(R) Tumor Paraffin 512006 Specimen Type Pending
512014 Reveal(R) Tumor Paraffin 512007 # of Genotyping Targets Pending
512014 Reveal(R) Tumor Paraffin 512008 Array Type Pending
512014 Reveal(R) Tumor Paraffin 512009 Diagnosis Pending
512014 Reveal(R) Tumor Paraffin 512010 Interpretation Pending
512014 Reveal(R) Tumor Paraffin 512011 Director Review Pending

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