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Microarray-Products of Conception (POC) Reveal® FFPE, Data Transfer
- Microarray Oncology
- Reveal® SNP Microarray-Products of Conception (POC)
- SNP Array
Detects chromosomal imbalance that may be associated with fetal loss or solid tumors and is ideal for detection of complete or partial molar pregnancies.
The microarray will detect DNA copy-number changes at a threshold >1Mb for deletions, >2 Mb for duplications. Also will detect copy-neutral changes associated with uniparental disomy and identity by descent.
This assay does not detect balanced rearrangements and low level mosaicism, or tetraploidy.
This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).
Whole genome SNP copy number microarray analysis using Molecular Inversion Probe (MIP) technology optimized for highly degraded FFPE samples.
Formalin fixed paraffin embedded (FFPE) tissue; fixed cell pellets
One paraffin block or ten 10-micron thick section slides
Sufficient sample to obtain enough DNA to run microarray
FFPE specimen should be fixed in 10% neutral-buffered formalin or formaldehyde. Cell pellet should be fixed in 3:1 methanol:acetic acid.
Causes for Rejection
Improperly embedded preparation; decalcified bone or bone core
Pertinent medical findings should accompany the test request form. Please direct questions to genetic customer service at 800-345-4363.
This assay is not approved for patients of New York State physicians.