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Venous Thrombosis Profile (Esoterix)
Activated partial thromboplastin time (aPTT); anticardiolipin antibodies IgG, IgM; antithrombin activity; β2-glycoprotein I, IgA, IgG, IgM; dilute Russell's viper venom time (dRVVT) confirm seconds; dilute Russell's viper venom time (dRVVT) ratio; dilute Russell's viper venom time (dRVVT) screen seconds; factor II gene mutation; factor VIII activity; hexagonal phospholipid neutralization; homocysteine; protein C activity (chromogenic); protein C resistance with factor V deficiency; protein S antigen, free
See individual tests.
Serum, plasma, and whole blood
Three 2-mL platelet-poor, frozen citrated plasma tubes, 5 mL whole blood, and 2 mL frozen serum
Plasma must be separated from cells within 45 minutes of venipuncture. Plasma must be centrifuged a second time before being placed in plastic transport tubes. Freeze within two hours and keep frozen until testing is performed. Allow gel-barrier tube or red-top tube to clot, centrifuge, and remove serum from cells within one hour. Send serum in plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Freeze serum and plasma. Maintain whole blood at room temperature; stable for seven days.
Causes for Rejection
Noncitrated plasma; gross hemolysis; fibrin clot; clotted samples if adequate DNA not obtained
Informed consent is required for New York patients. Test will reflex to Factor V Leiden Gene Mutation if APCR is abnormal. If abnormal, aPTT will reflex to Immediate aPTT Mixing Studies. If reflex test is performed, concomitant CPT codes/charges will apply.