Rapid Plasma Reagin (RPR), Quantitation

CPT: 86593
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Test Details

Synonyms

  • Nontreponemal Test
  • Syphilis Serology

Test Includes

Titer

Use

Serological non-treponema-specific test for syphilis used to screen for syphilis infection and to determine the effectiveness of treatment.

Limitations

False-positive reactions occur due to pregnancy, drug addiction, collagen vascular disease, and advanced age. In addition, false-positive results have been noted in the presence of numerous nonsyphilis infectious diseases, including HCV infection,1 inflammatory states, or in individuals who have been recently vaccinated against influenza virus.

Methodology

Charcoal flocculation

Reference Interval

Nonreactive

Specimen Requirements

Specimen

Serum

Volume

1 mL

Minimum Volume

0.5 mL

Container

Red-top tube or gel-barrier tube

Storage Instructions

Room temperature

Stability Requirements

Temperature

Period

Room temperature

7 days

Refrigerated

7 days

Frozen

7 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination; plasma specimen

Clinical Information

Footnotes

1. Thomas DL, Rompalo AM, Zenilman J, Hoover D, Hook EW 3rd, Quinn TC. Association of hepatitis C virus infection with false-positive tests for syphilis. J Infect Dis. 1994 Dec; 170(6):1579-1581. 7527828

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
006460 Rapid Plasma Reagin, Quant 31147-2 006460 Rapid Plasma Reagin, Quant 31147-2

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The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf