Neuroblastoma Monitor Profile

CPT: 82728; 84275; 86316
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Test Details

Test Includes

Ferritin; lipid-associated sialic acid (LASA), serial monitor report; neuron-specific enolase (NSE), serial monitor report

Use

Monitor the course of neuroblastoma, patient response to treatment, and disease recurrence

Limitations

This profile should not be used as a diagnostic or screening test for cancer. The LASA and NSE tests may be considered by Medicare and other carriers as investigational and, therefore, may not be payable as a covered benefit for patients.

Methodology

See individual tests.

Specimen Requirements

Specimen

Serum

Volume

4 mL

Minimum Volume

2 mL

Container

Red-top tube or gel-barrier tube

Collection

If a red-top tube is used, transfer separated serum to a plastic transport tube.

Storage Instructions

Refrigerate

Causes for Rejection

Gross hemolysis; whole blood specimen; recently administered isotopes

Clinical Information

Special Instructions

The account must submit the patient's Social Security number to monitor. Values obtained with different assay methods should not be used interchangeably in serial testing. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy.

This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to ask all patients who may be indicated for this test about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
485052 Neuroblastoma Monitor Profile 480114 Ferritin ng/mL 2276-4
485052 Neuroblastoma Monitor Profile 480133 Lipid-Associated Sialic Acid mg/dL 2943-9
485052 Neuroblastoma Monitor Profile 480001 Serial Monitoring N/A
485052 Neuroblastoma Monitor Profile 480138 Neuron Specific Enolase ng/mL 15060-7
485052 Neuroblastoma Monitor Profile 000000 Serial Monitoring N/A

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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf