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- Mn, Plasma
Evaluate industrial exposure
In evaluating toxicity, the serum level may have returned to normal while neurological damage persists. In evaluating possible deficiency states, the human deficiency syndrome is poorly defined, making interpretation difficult. Levels are reportedly reduced mildly in epilepsy, and raised in hepatitis or jaundice. Manganese levels are 60% lower than normal in hemodialysis patients.
Inductively-coupled plasma/mass spectrometry (ICP/MS)
Environmental exposure: <2.5 μg/L
Toxic exposure may occur from dry cells, fungicide (maneb), and in the steel industry or chemical industry. Manganese is present in the coloring agents for glass and soap, in paints, varnish, enamel, and in linoleum. It is used in the manufacture of chlorine gas and now in lead-free gasoline. Industrial manganese poisoning has been recognized since 1837. Some water supplies are sufficiently contaminated by manganese that endemic psychiatric and neurological disease is present.
Separate plasma immediately, and transfer to a certified metal-free plastic transport tube (PeopleSoft N° 111166) for shipment to the laboratory.
Causes for Rejection
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|071589||Manganese, Plasma||5683-8||071589||Manganese, Plasma||ug/L||5683-8|