Lung, Small-cell Cancer Monitor Profile

CPT: 82378; 84275; 86316
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Test Details

Test Includes

Carcinoembryonic antigen (CEA), serial monitor report; lipid-associated sialic acid (LASA), serial monitor report; neuron-specific enolase (NSE), serial monitor report


Monitor the course of small-cell lung cancer, patient response to treatment, and disease recurrence


This profile should not be used as a diagnostic or screening test for cancer. The LASA and NSE may be considered by Medicare and other carriers as investigational and, therefore, may not be payable as a covered benefit for patients.


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Specimen Requirements




4 mL

Minimum Volume

2 mL


Red-top tube or gel-barrier tube


If a red-top tube is used, transfer separated serum to a plastic transport tube.

Storage Instructions


Causes for Rejection

Hemolysis; whole blood specimen; recently administered isotopes

Clinical Information

Special Instructions

The account must submit the patient's Social Security number to monitor. State on the request form whether the patient is a smoker or nonsmoker. Values obtained with different assay methods should not be used interchangeably in serial testing. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
485177 Lung, Small Cell Ca Monitor 002169 CEA ng/mL 2039-6
485177 Lung, Small Cell Ca Monitor 480138 Neuron Specific Enolase ng/mL 15060-7
485177 Lung, Small Cell Ca Monitor 480133 Lipid-Associated Sialic Acid mg/dL 2943-9

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The LOINC® codes are copyright © 1994-2018, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at Additional information regarding LOINC® codes can be found at, including the LOINC Manual, which can be downloaded at