Liver Cancer Monitor Profile

CPT: 82105; 84275; 86301
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Test Details

Test Includes

α-Fetoprotein (AFP), serial monitor report; CA 19-9, serial monitor report; lipid-associated sialic acid (LASA), serial monitor report


Monitor the course of liver cancer, patient response to treatment, and disease recurrence


This profile should not be used as a diagnostic or screening test for cancer. The LASA test may be considered by Medicare and other carriers as investigational and, therefore, may not be payable as a covered benefit for patients.


See individual tests.

Specimen Requirements


Serum (preferred) or plasma


4 mL

Minimum Volume

2 mL


Red-top tube, gel-barrier tube, lavender-top (EDTA) tube, or green-top (heparin) tube


If a red-top tube or plasma is used, transfer separated serum or plasma to a plastic transport tube.

Storage Instructions


Stability Requirements



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Gross hemolysis; whole blood specimen

Clinical Information

Special Instructions

The account must submit the patient's Social Security number to monitor. Values obtained with different assay methods should not be used interchangeably in serial testing. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy.

This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to ask all patients who may be indicated for this test about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
485060 Liver Cancer Monitor Profile 002266 AFP, Serum, Tumor Marker ng/mL 53962-7
485060 Liver Cancer Monitor Profile 002282 CA 19-9 U/mL 24108-3
485060 Liver Cancer Monitor Profile 480001 Serial Monitoring N/A
485060 Liver Cancer Monitor Profile 480002 Serial Monitoring N/A
485060 Liver Cancer Monitor Profile 480133 Lipid-Associated Sialic Acid mg/dL 2943-9
485060 Liver Cancer Monitor Profile 000000 Serial Monitoring N/A

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