Human Immunodeficiency Virus 1 (HIV-1) GenoSure Archive®

CPT: Call 800-222-7566, ext 6-8400, for coding.
Updated on 11/30/2017
Print Share

Test Details

Synonyms

  • Cell-associated Viral DNA
  • HIV-1 Genotype
  • Resistance Analysis

Use

Detect resistance of HIV-1 to protease, reverse transcriptase, and integrase inhibitors in cell-associated viral DNA.

Limitations

This procedure should be used for patients with documented HIV-1 infection and undetectable viral load or low level viremia.

Methodology

Polymerase chain reaction (PCR) amplification and next generation DNA sequencing

Specimen Requirements

Specimen

Whole blood, frozen

Volume

4 mL

Container

Lavender-top (EDTA) tube

Collection

Collect specimen in lavender-top (EDTA) tube. Do not centrifuge. Ship frozen. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions

Freeze.

Causes for Rejection

Quantity not sufficient for analysis; heparinized plasma; nonfrozen specimen

Clinical Information

References

Günthard HF, Aberg JA, Eron JJ, et al. Antiretroviral treatment of adult HIV infection: 2014 recommendations of the International Antiviral Society-USA Panel. JAMA. 2014 Jul 23-30; 312(4):410-425. 25038359
Hurt C. Transmitted resistance to HIV integrase strand-transfer inhibitors: Right on schedule. Antivir Ther. 2011; 16(2):137-140. 21447861
Panel on Antiretroviral Guidelines for Adults and Adolescents—A Working Group of the Office of AIDS Research Advisory Council (OARAC). Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents. Washington, DC: Department of Health and Human Services; May 1, 2014.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
551776 GenoSure Archive(SM) 551774 HIV GenoSure Archive PDF 80695-0
551776 GenoSure Archive(SM) 551777 HIV GenoSure Archive N/A
551776 GenoSure Archive(SM) 551778 HIV GenoSure Archive 80693-5
551776 GenoSure Archive(SM) 551779 HIV GenoSure Archive Interp 80694-3
Reflex Table for HIV GenoSure Archive
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 551781 HIV GSArchive 551781 HIV GSArchive N/A
Reflex Table for HIV GenoSure Archive
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 551782 HIV GSArchive Interp 551782 HIV GSArchive Interp N/A

For Providers

Please login to order a test.

 

© 2017  Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf