Hepatitis Profile X (HBV Prevaccination Profile)

CPT: 86704; 86705; 86706; 87340
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Test Details


  • HBV Prevaccination (Profile X)

Test Includes

Hepatitis B core antibody (anti-HBc), IgM; hepatitis B core antibody (anti-HBc), total; hepatitis B surface antibody (anti-HBs); hepatitis B surface antigen (HBsAg)


Determine prior HBV infection (and/or immunity) and define individuals with no immunity as candidates for vaccines


See individual tests.

Specimen Requirements


Serum or plasma


4 mL

Minimum Volume

2 mL (Note: This volume does not allow for repeat testing.)


Red-top tube, gel-barrier tube, or lavender-top (EDTA) tube


If tube other than a gel-barrier tube is used, transfer separated serum or plasma to a plastic transport tube.

Storage Instructions

Room temperature

Stability Requirements



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Non-EDTA plasma specimen; PST gel-barrier tube

Clinical Information

Special Instructions

This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to ask all patients who may be indicated for this test about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
235473 HBV Prevaccination (Profile X) 006510 HBsAg Screen 5196-1
235473 HBV Prevaccination (Profile X) 016881 Hep B Core Ab, IgM 24113-3
235473 HBV Prevaccination (Profile X) 006718 Hep B Core Ab, Tot 13952-7
235473 HBV Prevaccination (Profile X) 006408 Hep B Surface Ab, Qual 22322-2
Reflex Table for HBsAg Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 016105 HBsAg Confirmation 016105 HBsAg Confirmation 7905-3

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