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- Antibody to Hepatitis B Surface Antigen
Hepatitis B surface antibody (anti-HBs) level can be measured to determine if vaccination is needed. Following a vaccination regimen, anti-HBs can be measured to determine if protective immunity has been achieved.
Presence of anti-HBs is not an absolute indicator of resolved hepatitis infection nor of protection from future infection. Since there are different serologic subtypes of hepatitis B virus, it is possible (and has been reported) for a patient to have antibody to one surface antigen type and to be acutely infected with a virus of a different subtype. Thus, a patient may have coexisting HBsAg and anti-HBs. Transfused individuals or hemophiliacs receiving plasma components may give false-positive tests for antibody to hepatitis B surface antigen.
Immunochemiluminometric assay (ICMA)
• Inconsistent with immunity: 0.0−9.9 mIU/mL
• Consistent with immunity: >9.9 mIU/mL
Serum or plasma
0.5 mL (Note: This volume does not allow for repeat testing.)
Red-top tube, gel-barrier tube, or lavender-top (EDTA) tube
If tube other than a gel-barrier tube is used, transfer separated serum or plasma to a plastic transport tube.
Causes for Rejection
Non-EDTA plasma specimen; PST gel-barrier tube
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|006530||Hepatitis B Surf Ab Quant||16935-9||006531||Hepatitis B Surf Ab Quant||mIU/mL||16935-9|