Helicobacter pylori Antibodies, IgG

CPT: 86677
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Test Details

Synonyms

  • Anti-Campylobacter Antibodies
  • Anti-H pylori, IgG

Test Includes

Quantitative result for IgG

Use

Aid in the diagnosis of H pylori infection; determine the cause of chronic type B gastritis or ulcers of the stomach or duodenum. Although earlier ELISA tests for IgG antibodies to H pylori had poor specificity, more recent studies have shown both high sensitivity (96%) and high specificity for H pylori associated with chronic gastritis. H pylori serology has become a standard tool for investigating the epidemiology of H pylori infections.

Methodology

Chemiluminescence

Reference Interval

• Negative: <0.9 units/mL

• Indeterminate: 0.9−1.0 units/mL

• Positive: >1.0 units/mL

Specimen Requirements

Specimen

Serum

Volume

1 mL

Minimum Volume

0.5 mL

Container

Red-top tube or gel-barrier tube

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination

Clinical Information

References

Kosunen TU, Seppälä K, Sarna S, Sipponen P. Diagnostic value of decreasing IgG, IgA, and IgM antibody titres after eradication of Helicobacter pylori.Lancet. 1992 Apr 11; 339(8798):893-895. 1348298
Thomson ABR. Helicobacter pylori and gastroduodenal pathology. Can J Gastroenterol. 1993; 7(4):353-358.
von Wulffen H. An assessment of serological tests for the detection of Helicobacter pylori.Eur J Clin Microbiol Infect Dis. 1992 Jul; 11(7):577-582.1396763

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
162289 H. pylori, IgG Abs 5176-3 162289 H. pylori, IgG Abs U/mL 5176-3

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