Fluoride, Urine

CPT: 82570; 82735
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Test Details


  • F, Urine
  • Sodium Fluoride

Test Includes

Creatinine, urine; fluoride, urine; fluoride:creatinine ratio


Monitor chronic exposure to fluoride


Ion-selective electrode (ISE) potentiometry

Reference Interval

Environmental exposure: 0.2−3.2 mg/L

Occupational exposure: BEI® (sampling time is prior to shift): 3.00 mg/g creatinine;1 BEI® (sampling time is end of the shift): 10.00 mg/g creatinine1

Additional Information

BEI® are reference values intended as guidelines for evaluation of occupational exposure. BEI® represent biological levels of chemicals that correspond to workers with inhalation exposure equivalent to the threshold limit value (TLV®) of the chemicals. TLVs refer to the airborne concentrations of substances and represent conditions under which it is believed that nearly all workers may be repeatedly exposed, day after day, without adverse health effects.1

Specimen Requirements


Urine (random)


5 mL

Minimum Volume

2.2 mL


Plastic urine container, no preservative. Do not use glass container.


Sampling time is prior to shift or end of shift for industrial monitoring. Inorganic analytes with timing “end of shift” (meaning the last two hours of exposure) or “prior to next shift” are eliminated rapidly with a half-life less than five hours. Such analytes do not accumulate in the body and, therefore, their timing is critical only in relation to the exposure and postexposure periods.

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Specimen received in a glass container.

Clinical Information

Special Instructions

Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. If both urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing.


1. TLVs and BEIs, Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices 2004, American Conference of Governmental Industrial Hygienists (ACGIH).


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
070052 Fluoride, Urine 070053 Fluoride, Urine mg/L 5650-7
070052 Fluoride, Urine 723280 Creatinine(Crt),U g/L 2161-8
070052 Fluoride, Urine 070056 Fluoride/Crt Ratio mg/g creat 13475-9

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