Endomysial Antibody, IgA

CPT: 86255
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Test Details

Use

Tissue transglutaminase is the autoantigen recognized by endomysial antibody in celiac disease.1

Methodology

Indirect fluorescent antibody (IFA)

Specimen Requirements

Specimen

Serum

Volume

1 mL

Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube or gel-barrier tube

Storage Instructions

Refrigerate

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Lipemia; hemolysis; microbially-contaminated sera

Clinical Information

Footnotes

1. Dieterich W, Ehnis T, Bauer M, et al. Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat Med. 1997 Jul; 3(7):797-801.9212111

References

Biagi F, Pezzimenti D, Campanella J, Vadacca GB, Corazza GR. Endomysial and tissue transglutaminase antibodies in coeliac sera: A comparison not influenced by previous serological testing. Scand J Gastroenterol. 2001 Sep; 36(9):955-958.11521986
National Institute of Health Consensus Development Conference Statement on Celiac Disease. NIH Consens State Sci Statements. 2004 Jun 28-30; 21(1):1-23.17308551

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
164996 Endomysial Antibody IgA 10362-2 164997 Endomysial Antibody IgA 10362-2

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The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf