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- Brain Cancer
- Breast Cancer
- Lung Cancer
Confirmation/identification of cancer-related alterations (for lung and brain cancer)
This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).
Fluorescence in situ hybridization (FISH)
High EGFR copy number or ratio of EGFR:control >2.0 detected by FISH has been shown to correlate with response, progression-free survival, and overall survival after treatment with EGFR TKIs in patients with non−small-cell lung cancer (NSCLC).1
Three slides of 4- or 5-micron FFPE sections with tumor. Blood or paraffin block (acceptable at an additional charge).
Three slides of 4- or 5-micron thick with tumor or 10 mL blood (adult), 5 mL blood (pediatric)
Two slides of 4- or 5-micron thick with tumor or 5 mL blood (adult), 1 mL blood (pediatric)
Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal
Transport to the testing lab at room temperature; use a cool pack or LabCorp transport kit. Do not allow sample to freeze.
Maintain specimen at room temperature.
Causes for Rejection
Broken or dirty slides; excessive cellular debris or stained slides; decalcified bone cores; frozen specimen; no tumor submitted
There will be an additional charge for processing paraffin block samples or for samples that require culture.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|510355||EGFR Oncology FISH||511736||Specimen Type||31208-2|
|510355||EGFR Oncology FISH||511737||Cells Counted||62361-1|
|510355||EGFR Oncology FISH||511738||Cells Analyzed||62360-3|
|510355||EGFR Oncology FISH||510353||FISH Result||48674-6|
|510355||EGFR Oncology FISH||511739||Interpretation||62365-2|
|510355||EGFR Oncology FISH||510356||Director Review:||48672-0|
|510355||EGFR Oncology FISH||512123||80563-0|