Bismuth, Whole Blood

CPT: 83018
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Expected Turnaround Time

3 - 4 days

Related Information

Related Documents

Specimen Requirements


Whole blood


7 mL

Minimum Volume

1.1 mL


Royal blue-top (EDTA) tube; submit original tube.

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Clotted specimen

Test Details


Monitor exposure to bismuth


This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.


Inductively-coupled plasma/mass spectrometry (ICP/MS)

Reference Interval

Normal: <10 μg/L

Additional Information

Bismuth poisoning through acute exposure is generally associated with the ingestion of soluble bismuth compounds as encountered in the therapeutic application of bismuth. Symptoms of acute poisoning often begin with foul breath and stomatitis and may progress to malaise, nausea, weight loss, and depression. Chronic bismuth exposure, which is typically attributed to inhalation, was generally evidenced by “tellurium breath,” but no adverse health effects were noted.1

Bismuth is employed in the production of low-melting alloys. It is also added to steel and iron to produce castings that are more easily machined. Bismuth is widely employed in the manufacture of ceramics and glass. The primary US source of bismuth is as a byproduct of the refining of lead and copper ores. Bismuth applications outside of industry include certain over-the-counter drugs intended as aids for gastrointestinal disturbances, as well as the pearlescent white coloring matter used in some lipsticks, powders, and fingernail enamels.


1. Carson BL, Ellis HV III, McCann JL. Toxicology and Biological Monitoring of Metals in Humans: Including Feasibility and Need. Chelsea, MI: Lewis Publishers;1986.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
706515 Bismuth, Blood 8161-2 706515 Bismuth, Blood ug/L 8161-2

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