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For hours, walk-ins and appointments.Anti-Nuclear Antibodies by Indirect Fluorescent Antibody (IFA), Cerebrospinal Fluid (RDL)
CPT:
86038
Expected Turnaround Time
5 - 7 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Cerebrospinal fluid
Volume
2 mL
Minimum Volume
0.5 mL (Note: This volume does not allow for repeat testing.)
Container
Sterile transport tube
Collection
Collect cerebrospinal fluid in sterile transport tube.
Storage Instructions
Refrigerate or freeze.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 7 days |
Refrigerated | 14 days |
Frozen | 60 days |
Freeze/thaw cycles | Stable x1 |
Causes for Rejection
Grossly hemolyzed, bacterial contamination, lipemic, icteric, incorrect specimen types
Test Details
Use
ANA are commonly found in a variety of autoimmune diseases. Antibody frequency increases with age in apparently healthy people. ANA patterns on HEp-2 slides provide only general clues about particles (chromatin, nucleosomes, and spliceosomes). ANA patterns (other than centromere pattern) are not reliably correlated with the presence of specific antibodies and must be further evaluated by EIA using individual ENA antigens.
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Indirect Fluorescent Antibody (IFA)
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 520145 | ANA by IFA, CSF (RDL) | 63294-3 | 520146 | ANA by IFA, CSF (RDL) | 63294-3 |
| Reflex Table for ANA by IFA, CSF (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520258 | ANA Titer and Pattern CSF | 520266 | Homogeneous Pattern | Pending | |
| Reflex Table for ANA by IFA, CSF (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520258 | ANA Titer and Pattern CSF | 520267 | Nucleolar Pattern | Pending | |
| Reflex Table for ANA by IFA, CSF (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520258 | ANA Titer and Pattern CSF | 520268 | Speckled Pattern | Pending | |
| Reflex Table for ANA by IFA, CSF (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520258 | ANA Titer and Pattern CSF | 520269 | Centromere Pattern | Pending | |
| Reflex Table for ANA by IFA, CSF (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520258 | ANA Titer and Pattern CSF | 520270 | Spindle Apparatus Pattern | Pending | |
| Reflex Table for ANA by IFA, CSF (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520258 | ANA Titer and Pattern CSF | 520271 | Nuclear Membrane Pattern | Pending | |
| Reflex Table for ANA by IFA, CSF (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520258 | ANA Titer and Pattern CSF | 520272 | Midbody Pattern | Pending | |
| Reflex Table for ANA by IFA, CSF (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520258 | ANA Titer and Pattern CSF | 520273 | Nuclear Dot Pattern | Pending | |
| Reflex Table for ANA by IFA, CSF (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520258 | ANA Titer and Pattern CSF | 520274 | PCNA Pattern | Pending | |
| Reflex Table for ANA by IFA, CSF (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520258 | ANA Titer and Pattern CSF | 520275 | Centriole Pattern | Pending | |
| Reflex Table for ANA by IFA, CSF (RDL) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 520258 | ANA Titer and Pattern CSF | 520276 | Note: | Pending | |
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