Anti-Proliferating Cell Nuclear Antibodies by Indirect Fluorescent Antibody (IFA) (RDL)

TEST: 520121
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CPT: 86255
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Synonyms

  • Anti-Proliferating Cell Nuclear Ab

Expected Turnaround Time

7 - 14 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

Specimen Requirements

Specimen

Serum

Volume

1 mL

Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube or gel-barrier tube

Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions

Refrigerate or freeze.

Stability Requirements

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types

Test Details

Use

Anti-proliferating cell nuclear antibodies (PCNA) are found in <10% of SLE patients. The presence of PCNA is associated with renal, CNS involvement and thrombocytopenia in SLE; PCNA titers are elevated prior to development of proteinuria and decrease following corticosteroid treatment.

Methodology

Indirect Immunofluorescence (IFA)

Reference Interval

Negative

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
520121 Anti-PCNA by IFA (RDL) 47074-0 520122 Anti-PCNA by IFA (RDL) 47074-0

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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf