PrEP Use Only: eGFR With Creatinine

TEST: 100781
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CPT: 82565
To be determined. Updates will be made when available.
82565
Updated on 03/20/2024
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Synonyms

  • Pre-exposure prophylaxis eGFR

Special Instructions

This is a PrEP-specific test number to ensure reimbursement per CARES Act. It contains a CPT code modifier.

Related Documents

Specimen Requirements

Specimen

Serum (preferred) or plasma

Volume

1 mL

Minimum Volume

0.7 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube, gel-barrier tube or green-top (lithium heparin) tube. Do not use oxalate, EDTA or citrate plasma.

Collection

If a red-top tube or plasma tube is used, transfer separated serum or plasma to a plastic transport tube.

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Hemolysis; improper labeling

Test Details

Use

HIV PrEP use only: This test monitors kidney function using eGFR and creatinine in individuals who are eligible for or who are receiving pre-exposure prophylaxis for HIV (PrEP). Per current recommendations, serum creatinine should generally be measured prior to or at the time of initiating PrEP. Individuals with an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73m2 are not candidates for TDF-FTC; those with an eGFR <30 mL/min/1.73m2 should not receive TDF-FTC or TAF-FTC.

Methodology

Kinetic Jaffe

References

Centers for Disease Control and Prevention (CDC). Pre-Exposure Prophylaxis (PrEP). CDC website: https://www.cdc.gov/hiv/risk/prep/index.html. Updated July 2022. Accessed February 2024.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
100781 PrEP: eGFR w/Creatinine 45066-8 001370 Creatinine mg/dL 2160-0
100781 PrEP: eGFR w/Creatinine 45066-8 100779 eGFR mL/min/1.73 98979-8

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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf