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Rheumatology Services

Full-Service Solutions for Rheumatologists

Broad capabilities in Autoimmune Testing

Labcorp offers a comprehensive testing menu and numerous service benefits to support the needs of a rheumatology practice. With the acquisition of certain assets of RDL Reference Laboratory, Labcorp now offers the full range of autoimmune testing services that RDL has offered for more than 40 years. Labcorp is fully committed to continuing RDL’s legacy of providing innovative autoimmune testing services to aid with the diagnosis, treatment, and management of complex autoimmune syndromes.

Testing Services

Labcorp features a full-service offering to support physicians in the evaluation of patients for rheumatic diseases.

Labcorp’s leading services include:

  • Novel RA Markers: 14-3-3 eta, Anti-CEP-1, Anti-Sa, and Anti-CarP markers that provide increased sensitivity for RA diagnosis.
  • MyoMarker™ myositis testing profiles includes both Myositis-Specific Antibodies (MSA) and Myositis-Associated Antibodies (MAA).
  • ANA by IFA Profiles: Reflex and Non-reflex options. Negative titers confirmed with Anti-Ro Ab.
  • Anti-Dense Fine Speckled Protein 70 kDA (DFS70) Ab: may help identify individuals who do not have an ANA-associated Autoimmune Rheumatic Disease (AARD).
  • Additional Profiles: Systemic sclerosis, Sjogren's syndrome, and Interstitial Lung Disease.
  • Methotrexate (MTX) Polyglutamates Test: Monitors MTX polyglutamates to determine effectiveness of MTX therapy.
  • QuantiFERON®-TB Gold Plus: Tuberculosis (TB) blood test allows for screening in a single office visit and is appropriate for immune-compromised patients and those considering biologics therapy.
  • DoseASSURE™, Labcorp’s portfolio of biologics assays that monitor drug concentration and antibody levels to help optimize dosing and frequency: Adalimumab, Certolizumab, Etanercept, Golimumab, Infliximab, Rituximab, Ustekinumab.

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Labcorp Benefits

  • Multiple connectivity options
  • More than 1900 patient service centers nationwide
  • Extensive network of managed care health plans
  • Experienced medical affairs professionals are available for consultation and educational programs
  • Rheumatology Services Hotline: 800-338-1918

Rheumatology Test Portfolio

Test Name Test No.
ANA 12 Plus Profile (RDL)
ANA 12 Plus Profile, Do All (RDL)
Anti-Carbamylated Protein (CarP) Antibody
Anti-Dense Fine Speckled Protein 70 kDa (DFS70) Ab
Anti-dsDNA (double stranded) Ab by Farr RIA method (RDL)
Hydroxychloroquine, Whole Blood
Interstitial Lung Disease Profile (RDL)
Methotrexate Polyglutamates
Myomarker® 3 Plus Profile (RDL)
Myomarker® 3 Profile (RDL)
14.3.3 eta, Rheumatoid Arthritis
Pre-Biologic Screening Profile
RAdx5 Profile (RDL)
SeroNeg RAdx3 Profile (RDL)
Sjogren's Profile Plus (RDL)


— Adalimumab and Anti-Adalimumab Antibody (Serial Monitor), DoseASSURE™ ADL

— Certolizumab and Anti-Certolizumab Antibody, DoseASSURE™ CTZ

— Etanercept and Anti-Etanercept Antibody (Serial Monitor), DoseASSURE™ ETN

— Golimumab and Anti-Golimumab Antibody, DoseASSURE™ GOL

— Infliximab and Anti-Infliximab Antibody (Serial Monitor), DoseASSURE™ IFX

— Rituximab and Anti-Rituximab Antibody, DoseASSURE™ RTX

— Ustekinumab and Anti-Ustekinumab Antibody, DoseASSURE™ UST

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  1. Carrier N, Marotta M, de Brum-Fernandes A, Liang P, Masetto A, Menard HA, et al. Serum levels of 14-3-3η protein supplement C-reactive protein and rheumatoid arthritis-associated antibodies to predict clinical and radiographic outcomes in a prospective cohort of patients with recent-onset inflammatory polyarthritis. Arthritis Research & Therapy. 2016; 18(37) 1-14.