Aldolase is an enzyme that helps convert glucose into energy. It is found throughout the body but is primarily found in high levels in muscle tissue.
Because aldolase levels are elevated in the bloodstream when a person has muscle damage, the aldolase blood test may be ordered to diagnose and monitor certain conditions related to skeletal muscle. It largely has been replaced by other muscle enzyme tests, especially CK (creatine kinase). However, a minority of people with muscle pain may have an elevated aldolase level even though their CK is normal. Therefore, the test may sometimes be requested by rheumatologists in addition to CK.
© 2017 American Association for Clinical Chemistry, republished from Lab Tests Online.*
Descriptions of clinical laboratory tests were originally prepared for use on Lab Tests Online, an award-winning patient education website on clinical laboratory testing. Lab Tests Online is produced by the American Association for Clinical Chemistry (AACC), a global scientific and medical professional organization dedicated to clinical laboratory science and its application to healthcare. The Lab Tests Online website is developed in collaboration with other laboratory professional societies and is funded in part through corporate sponsorships.