Interleukin-10, Plasma

CPT: 83520
Print Share


  • IL-10
  • IL10

Expected Turnaround Time

4 - 7 days

Related Documents

Specimen Requirements




0.5 mL

Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)


Lavender-top (EDTA) tube


Separate plasma from cells. Transfer plasma to a plastic transport tube.

Storage Instructions

Refrigerate; stable for 14 days. Stable at room temperature or frozen for 14 days. Freeze/thaw cycles x3.

Causes for Rejection

Gross hemolysis; gross lipemia

Test Details


Interleukin-10 (IL-10) is an important suppressor of immune responses1-3 In vitro studies indicate that IL-10 directly inhibits IL-2 and IL-5 production by TH1 and TH2 cells. IL-10 acts as an immunosuppressor of antigen presenting cells (APC). IL-10 suppresses epidermal Langerhans cell APC function, monocyte chemokines expression, and the bactericidal responses of macrophages. A number of studies suggest that IL-10 plays a role in controlling inflammation, autoimmunity, and angiogenesis.


Results of this test are for research purposes only by the assay's manufacturer. The performance characteristics of this assay have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.


Enzyme-linked immunosorbent assay (ELISA)


1. Ding UZ, Fu S, Zamarin D, et al. Interleukin-10. In: Thomson AW, Lotze MT eds. Cytokine Handbook. 4th ed, vol 1. London, UK, and San Diego, Calif: Academic Press, Elsevier Science;2003:603-625.
2. Mosser DM, Zhang X. Interleukin-10: New perspectives on an old cytokine. Immunol Rev. 2008 Dec; 226:205-218. 19161426
3. Hedrich CM, Bream JH. Cell type-specific regulation of IL-10 expression In inflammation and disease. Immunol Res. 2010 Jul; 47(1-3):185-206. 20087682


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
140820 Interleukin-10, Plasma 26848-2 140821 Interleukin-10, Plasma pg/mL 26848-2

For Providers

Please login to order a test

Order a Test

© 2021 Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at Additional information regarding LOINC® codes can be found at, including the LOINC Manual, which can be downloaded at