Synonyms
- CXCL8
- IL-8
- IL8
Expected Turnaround Time
4 - 7 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
Related Documents
Specimen Requirements
Specimen
Plasma
Volume
0.5 mL
Minimum Volume
0.3 mL (Note: This volume does not allow for repeat testing.)
Container
Lavender-top (EDTA) tube
Collection
Separate plasma from cells. Transfer plasma transfer to a plastic transport tube.
Storage Instructions
Refrigerate; stable for seven days. Stable at room temperature for three days. Stable frozen for 14 days. Freeze/thaw cycles x2.
Causes for Rejection
Gross hemolysis; gross lipemia
Test Details
Use
Interleukin-8 (IL-8), a member if the neutrophil-specific CXC subfamily of chemokines, is a potent neutrophil chemotactic and activating factor.1 It is a primary inflammatory cytokine produced by many cells (including monocytes/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, astrocytes, and chondrocytes) in response to proinflammatory stimuli such as bacteria and viruses. IL-8 serves to attract neutrophils to the site of inflammation and to activate them.
Limitations
Results of this test are for research purposes only by the assay's manufacturer. The performance characteristics of this assay have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.
Methodology
Enzyme-linked immunosorbent assay (ELISA)
Footnotes
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 140818 | Interleukin-8, Plasma | 33211-4 | 140819 | Interleukin-8, Plasma | pg/mL | 33211-4 |
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