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Nocardia, Aerobic Actinomycetes Susceptibility (AST)−Broth Dilution

Test Number 182857
Test number copied
CPT 87186
Synonyms
  • Nocardia Susceptibility Testing
  • AFB Susceptibility Testing
  • Susceptibility Testing, Nocardia

Test Details

Methodology

Sensititre® broth microdilution (MIC)

Result Turnaround Time

14 - 28 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Information

Related Documents

Test Includes

Susceptibility testing for amikacin, amoxicillin/clavulanic acid, ceftriaxone, ciprofloxacin, clarithromycin, doxycycline, imipenem, linezolid, minocycline, moxifloxacin, trimethoprim/sulfamethoxazole, and tobramycin. MIC values will be reported with CLSI interpretive comments.

Use

Determine the susceptibility of Nocardia species and/or other aerobic Actinomycetes isolates to a profile of antimicrobial agents. Routine susceptibility testing of Nocardia isolates is recommended since the Nocardia genus contains a heterogeneous group of organisms that has variable antibiotic susceptibilities.

Limitations

Susceptibilities cannot be reported if the organism fails to grow in the test medium. Susceptibilities cannot be performed on mixed cultures.

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.

Specimen Requirements

Specimen

Nocardia species or other aerobic actinomycetes isolated from a primary clinical specimen, on a submitted conventional solid medium (ie, Lowenstein-Jensen [LJ] slant, Sabouraud dextrose [SAB] slant, or similar)

Volume

Pure culture isolate on a conventional solid medium

Container

Conventional medium, tightly sealed, in etiologic agent packaging

Storage Instructions

Maintain media at room temperature.

Causes for Rejection

Broken transport tube or vial; specimen received in expired transport medium; mixed culture; unlabeled culture or name discrepancy between specimen and request label

References

Clinical Laboratory Standards Institute (CLSI). Performance Standards for Susceptibility Testing of Mycobacteria, Nocardia spp., and Other Aerobic Actinomycetes. 1st ed. CLSI supplement M62. Wayne, PA: CLSI; 2018.
Clinical Laboratory Standards Institute (CLSI). Susceptibility Testing of Mycobacteria, Nocardia spp., and Other Aerobic Actinomycetes. 3rd ed. CLSI standard M24. Wayne, PA: CLSI; 2018.
Woods GL, Lin SYG, Brown BA, Desmond EP. Susceptibility Test Methods: Mycobacteria, Nocardia and Other Actinomycetes. Manual of Clinial Microbiology, 12th ed. 2018; 78:1398-1419.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
182857 Nocardia Susceptibility Broth 50545-3 182858 Organism ID N/A
182857 Nocardia Susceptibility Broth 50545-3 998537 Amikacin 5-Dec
182857 Nocardia Susceptibility Broth 50545-3 998538 Amoxicillin/CA 20-8
182857 Nocardia Susceptibility Broth 50545-3 998539 Ceftriaxone 141-2
182857 Nocardia Susceptibility Broth 50545-3 998540 Ciprofloxacin 185-9
182857 Nocardia Susceptibility Broth 50545-3 998541 Clarithromycin 189-1
182857 Nocardia Susceptibility Broth 50545-3 998216 Doxycycline 225-3
182857 Nocardia Susceptibility Broth 50545-3 998543 Imipenem 279-0
182857 Nocardia Susceptibility Broth 50545-3 998544 Linezolid 29254-0
182857 Nocardia Susceptibility Broth 50545-3 998545 Minocycline 335-0
182857 Nocardia Susceptibility Broth 50545-3 998217 Moxifloxacin 31037-5
182857 Nocardia Susceptibility Broth 50545-3 998547 Tobramycin 508-2
182857 Nocardia Susceptibility Broth 50545-3 998546 Trimethoprim/Sulfa 516-5
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code182858
Result Code NameOrganism ID
UofM
Result LOINCN/A
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code998537
Result Code NameAmikacin
UofM
Result LOINC5-Dec
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code998538
Result Code NameAmoxicillin/CA
UofM
Result LOINC20-8
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code998539
Result Code NameCeftriaxone
UofM
Result LOINC141-2
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code998540
Result Code NameCiprofloxacin
UofM
Result LOINC185-9
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code998541
Result Code NameClarithromycin
UofM
Result LOINC189-1
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code998216
Result Code NameDoxycycline
UofM
Result LOINC225-3
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code998543
Result Code NameImipenem
UofM
Result LOINC279-0
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code998544
Result Code NameLinezolid
UofM
Result LOINC29254-0
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code998545
Result Code NameMinocycline
UofM
Result LOINC335-0
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code998217
Result Code NameMoxifloxacin
UofM
Result LOINC31037-5
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code998547
Result Code NameTobramycin
UofM
Result LOINC508-2
Order Code182857
Order Code NameNocardia Susceptibility Broth
Order Loinc50545-3
Result Code998546
Result Code NameTrimethoprim/Sulfa
UofM
Result LOINC516-5
Reflex Table for Organism ID
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 000000 Antimicrobial Susceptibility 000000 Antimicrobial Susceptibility N/A
Reflex 1
Order Code000000
Order NameAntimicrobial Susceptibility
Result Code000000
Result NameAntimicrobial Susceptibility
UofM
Result LOINCN/A