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Rituximab and Anti-Rituximab Antibody, DoseASSURE™ RTX
This test includes Serial Monitoring.
Expected Turnaround Time
12 - 16 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
For more information, please view the literature below.
1 mL (Note: This volume does not allow for repeat testing.)
Gel-barrier tube, red-top tube, or serum transfer tube
Serum must be separated from cells within 45 minutes of venipuncture. Submit serum in a plastic transport tube. To avoid delays in turnaround time when requesting multiple test on frozen samples, please submit separate frozen specimens for each test requested.
Refrigerate or freeze
Causes for Rejection
Gross hemolysis; gross lipemia; icteric specimen
Therapeutic monitoring of rituximab and antidrug antibody development for individuals with non-Hodgkin's lymphoma (NHL), chronic lymphocytic leukemia (CLL), and rheumatoid arthritis. This test provides rituximab drug concentration as well as the level of anti-rituximab antibodies.
Failure of rituximab therapy may not always be due to the presence of anti-rituximab antibodies. Conversely, the absence of anti-rituximab antibodies does not guarantee positive response to treatment.
This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).
Electrochemiluminescence immunoassay (ECLIA); chemiluminescence immunoassay (CLIA)
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|504355||RTA Conc+RTA Ab||504356||Rituximab Drug Concentration||ug/mL||82467-2|
|504355||RTA Conc+RTA Ab||504357||Anti-Rituximab Antibody Level||ng/mL||82466-4|
|Reflex Table for Anti-Rituximab Antibody Level|
|Order Code||Order Name||Result Code||Result Name||UofM||Result LOINC|
|Reflex 1||000000||Serial Monitoring||000000||Serial Monitoring||N/A|