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Nontuberculous Slowly-growing Mycobacterium Susceptibility−Broth Dilution
- M kansasii Susceptibility Testing
- AFB Susceptibility Testing
- MOTT Susceptibility Testing
- Slow-grower Susceptibility Testing
Susceptibility testing for amikacin, ciprofloxacin, clarithromycin, ethambutol, linezolid, streptomycin, and sulfamethoxazole-trimethoprim
Determine the susceptibility of nontuberculous slowly-growing mycobacterial isolates to a profile of antimycobacterial agents. Interpretive categories for MICs are not yet available due to lack of clinical trial data that would indicate the clinical efficacy.1,2 For the unusual mycobacteria, susceptibility data is often useful as an aid in identification.
Susceptibilities cannot be reported if the organism fails to grow in the test medium. Susceptibilities cannot be performed on mixed cultures. An organism identification is required prior to reporting susceptibility results.
Results of this test are labeled for research purposes only by the assay's manufacturer. The performance characteristics of this assay have not been established by the manufacturer. The result should not be used for treatment or for diagnostic purposes without confirmation of the diagnosis by another medically established diagnostic product or procedure. The performance characteristics were determined by LabCorp.
Sensititre® broth microdilution (MIC)
Failure to take all drugs in a multidrug regimen can lead to a shift toward resistant organisms and treatment failure.3 Susceptibility testing to rifampin is the only drug currently recommended for primary susceptibility testing of M kansasii.2 Isolates susceptible to rifampin are susceptible to rifabutin.
Test results are not intended to be used as the sole means for patient management.
Slowly-growing mycobacteria, not M tuberculosis, isolated from a primary clinical specimen, on a submitted AFB conventional solid medium, or an AFB broth medium
Pure culture isolate on an AFB conventional solid medium or a minimum of 1 mL of AFB broth medium
Conventional or broth medium, tightly sealed, in etiologic agent packaging
Maintain media at room temperature.
Causes for Rejection
Specimen received in leaking or in broken transport tube or vial; specimen received in expired transport medium; mixed culture; unlabeled culture or name discrepancy between specimen and request label
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|182923||Slow Grower Broth Suscep.||182924||Organism ID||40699-1|
|182923||Slow Grower Broth Suscep.||998568||Amikacin||12-5|
|182923||Slow Grower Broth Suscep.||998569||Ciprofloxacin||185-9|
|182923||Slow Grower Broth Suscep.||998570||Clarithromycin||189-1|
|182923||Slow Grower Broth Suscep.||998571||Ethambutol||241-0|
|182923||Slow Grower Broth Suscep.||998572||Linezolid||29254-0|
|182923||Slow Grower Broth Suscep.||998573||Moxifloxacin||31037-5|
|182923||Slow Grower Broth Suscep.||998574||Rifampin||428-3|
|182923||Slow Grower Broth Suscep.||998576||Streptomycin||460-6|
|182923||Slow Grower Broth Suscep.||998577||Trimethoprim/Sulfa||516-5|
|182923||Slow Grower Broth Suscep.||182833||Please note:||N/A|
|Reflex Table for Organism ID|
|Order Code||Order Name||Result Code||Result Name||UofM||Result LOINC|
|Reflex 1||000000||Antimicrobial Susceptibility||000000||Antimicrobial Susceptibility||N/A|