Calculi, with Photograph

TEST: 910180
Test number copied
CPT: 82365
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Synonyms

  • Kidney Stone, gall stone, salivary stone

Expected Turnaround Time

4 - 6 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

Specimen Requirements

Specimen

Calculi

Container

30/50mL clean specimen container or capsule

Collection

Provide source (urinary, gall, salivary) of calculi. Avoid rejection and delayed processing by sending the stone completely dried in a clean container. Do not send gauze, filters, tape or Q-tips. Stones that are not received completely dried will result in delayed processing.

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Urine; stone analysis not performed on urine samples

Test Details

Use

Determine calculi composition, metabolic factors affecting stone formation, evaluation of patient with nephrolithiasis

Limitations

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.

Methodology

Infrared Spectroscopy

Additional Information

In the United States, the incidence of urinary tract calculi is common, with one person in 1000 requiring hospital care and treatment. A typical urinary calculus is composed of crystalline substances precipitated in the body. To ensure proper treatment and prevention of recurrences of urinary calculi, it is critical that the crystalline constituents of the stone be identified. Mandel describes 15 crystalline substances common in urinary calculi and subdivides them into six broad catagories.1,2

Calculi, Urinary

Chemical Name

Formula

Mineralogic Name

Calcium oxalate monohydrate

CaC2O4 • H2O

Whewelite

Calcium oxalate dihydrate

CaC2O4 • 2H2O (to 2 • 5H2O)

Weddellite

Magnesium hydrogen phosphate trihydrate

MgHPO4 • 3H2O

Newberyite

Magnesium ammonium phosphate hexahydrate

MgNH4PO4 • 6H2O

Struvite

Hydroxyapatite

Ca10(PO4)6 (OH)2

Hydroxyapatite

Carbonate-apatite

Ca10(PO4)6-x (OH)2-y (CO3)x+y

Carbonate-apatite

Calcium hydrogen phosphate dihydrate

CaHPO4 • 2H2O

Brushite

Uric acid

C5H4N4O3

Uric acid dihydrate

C5H4N4O3 • 2H2O

Ammonium acid urate

C5H3N4O3NH4

Sodium acid urate monohydrate

C5H3N4O3Na • H2O

Cystine

[-SCH2CHNH2COOH]2

Xanthine

C5H4N4O2

Footnotes

1. Mandel NS, Mandel IC, Kolbach-Mandel AM. Accurate stone analysis: the impact on disease diagnosis and treatment. Urolithiasis. 2017 Feb;45(1):3-9.27915396
2. Mandel N. Urinary tract calculi. Lab Med. 1986 Aug;17(8):449-458. doi: 10.1093/labmed/17.8.449

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
910180 Stone Analysis 74446-6 910037 Source 85793-8
910180 Stone Analysis 74446-6 910038 Color 9796-4
910180 Stone Analysis 74446-6 910039 Size mm 9802-0
910180 Stone Analysis 74446-6 910090 Weight mg 9804-6
910180 Stone Analysis 74446-6 910093 Composition N/A
910180 Stone Analysis 74446-6 910095 Calcium Oxalate Monohydrate % 38252-3
910180 Stone Analysis 74446-6 910094 Calcium Oxalate Dihydrate % 49500-2
910180 Stone Analysis 74446-6 910179 Calcium phosphate (hydroxyl) % N/A
910180 Stone Analysis 74446-6 910181 Calcium phosphate (carbonate) % 16267-7
910180 Stone Analysis 74446-6 910154 CaHPO4 (Brushite) % 40998-7
910180 Stone Analysis 74446-6 910096 Calcium Phosphate % 32137-2
910180 Stone Analysis 74446-6 910160 Calcium Carbonate % 32156-2
910180 Stone Analysis 74446-6 910097 MgNH4PO4 (Struvite) % 32143-0
910180 Stone Analysis 74446-6 910162 MgHPO4 (Newberyite) % 54440-3
910180 Stone Analysis 74446-6 910098 Uric Acid % 32149-7
910180 Stone Analysis 74446-6 910099 Uric Acid Dihydrate % 54436-1
910180 Stone Analysis 74446-6 910152 Ammonium Acid Urate % 38191-3
910180 Stone Analysis 74446-6 910153 Sodium Acid Urate % 54437-9
910180 Stone Analysis 74446-6 910184 2,8 Dihydroxyadenine % N/A
910180 Stone Analysis 74446-6 910185 Xanthine % 58036-5
910180 Stone Analysis 74446-6 910155 Cystine % 32138-0
910180 Stone Analysis 74446-6 910156 Cholesterol % 54438-7
910180 Stone Analysis 74446-6 910157 Calcium Bilirubinate % 54439-5
910180 Stone Analysis 74446-6 910186 Bilirubin % 74434-2
910180 Stone Analysis 74446-6 910187 Calcium Palmitate % N/A
910180 Stone Analysis 74446-6 910188 Calcium Stearate % N/A
910180 Stone Analysis 74446-6 910161 Triamterene % 43690-7
910180 Stone Analysis 74446-6 910189 Drug or Metabolite N/A
910180 Stone Analysis 74446-6 910163 Dried Blood % 49499-7
910180 Stone Analysis 74446-6 910164 Cellular Material % 56119-1
910180 Stone Analysis 74446-6 910192 Other component(s) N/A
910180 Stone Analysis 74446-6 910170 Comment 14638-1
910180 Stone Analysis 74446-6 910171 Comment 77202-0
910180 Stone Analysis 74446-6 910172 Photo N/A
910180 Stone Analysis 74446-6 910173 Comment: 77202-0
910180 Stone Analysis 74446-6 910176 Please note: N/A
910180 Stone Analysis 74446-6 910177 Disclaimer: N/A
910180 Stone Analysis 74446-6 910178 PDF 11502-2

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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf