Heroin Confirmation, Serum, Plasma, or Whole Blood

CPT: 80356; 80361
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  • 6-Acetylmorphine
  • Diacetylmorphine

Test Includes

6-Acetylmorphine (6-AM); morphine

Expected Turnaround Time

10 - 14 days

Specimen Requirements


Serum, plasma, or whole blood


7 mL

Minimum Volume

2 mL


Serum or plasma: red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended. Whole blood: Lavender-top (EDTA) tube, gray-top (sodium fluoride) tube, or green-top (heparin) tube


Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.

Storage Instructions

Refrigerate; specimen may also be frozen.

Causes for Rejection

Gel-barrier tubes

Test Details


Detect the presence of heroin metabolites


Chromatography with Mass Spectrometry


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
790560 Heroin, Serum/Plasma/WB 790569 Morphine ng/ml 74131-4
790560 Heroin, Serum/Plasma/WB 790567 6-Acetylmorphine 74130-6

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