Autoimmune Neuromuscular Profile

CPT: 83516(x3); 86235
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Synonyms

  • Neuromuscular antibodies

Expected Turnaround Time

14 - 21 days


Specimen Requirements


Specimen

Serum


Volume

4 mL


Minimum Volume

2 mL (Note: This volume does not allow for repeat testing.)


Container

Serum from a gel-barrier tube or red-top tube


Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.


Storage Instructions

Refrigerate or freeze.


Stability Requirements

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1


Test Details


Use

To evaluate the presence of 4 markers related to autoimmune neuromuscular disorders, Anti-cN-1A Ab for IBM, Anti-HMGCR Ab, Anti-Jo-1 Ab, and Anti-SRP Ab.

See the individual tests for further information on each one.


Limitations

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.


Methodology

Enzyme-linked immunosorbent assay (ELISA) and RIPA gel radiography


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
520310 Neuromuscular Profile 520062 Anti-cN-1A (NT5c1A) IBM (RDL) Units 96562-4
520310 Neuromuscular Profile 520058 Anti-HMGCR Ab (RDL) Units 95726-6
520310 Neuromuscular Profile 520033 Anti-Jo-1 Ab (RDL) Units 11565-9
520310 Neuromuscular Profile 520040 Anti-SRP Ab (RDL) 33921-8

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