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Maternal Cell Contamination

CPT: 81265
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Special Instructions

If a prenatal specimen (CVS or amniotic fluid) has not already been submitted to LabCorp for other testing, it must now be provided to complete maternal cell contamination (MCC) analysis. LabCorp buccal swab kits can be ordered using PeopleSoft No. 3177.

If cultured cells are needed, an additional 7-12 days may be required. Additional culture fee may be included.

Expected Turnaround Time

11 - 21 days

Specimen Requirements


Whole blood or LabCorp buccal swab kit (Buccal swab collection kit contains instructions for use of a buccal swab.), amniotic fluid, or chorionic villus sample (CVS) (Submission of maternal blood is required for fetal testing.)


7 mL whole blood or LabCorp buccal swab kit, 10 mL amniotic fluid, or 20 mg CVS

Minimum Volume

3 mL whole blood or two buccal swabs, 5 mL amniotic fluid, or 10 mg CVS


Lavender-top (EDTA) tube or yellow-top (ACD) tube or LabCorp buccal swab kit, sterile plastic conical tube, or two confluent T-25 flasks for fetal testing

Storage Instructions

Maintain specimen at room temperature or refrigerate.

Causes for Rejection

Frozen or hemolyzed specimen; quantity not sufficient for analysis; improper container

Test Details


Quality assurance for interpretation of prenatal molecular genetic test results


This test is not applicable in nonmaternity contexts.

Results of this test are for investigational purposes only. The performance characteristics of this assay have been determined by LabCorp. The result should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.


Analysis of short tandem repeat markers by polymerase chain reaction (PCR) and capillary electrophoresis


Shadravan F. Sizing precision and reproducibility studies of AmpFLP-STR® kits with ABI Prism® 3100 genetic analyzer. Proc Am Acad Forensic Sci. 2001; 7:26.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
511402 Maternal Cell Contamination 511401 Maternal Cell Contamination 59266-7
511402 Maternal Cell Contamination 511404 Method/Limitations 49549-9
511402 Maternal Cell Contamination 511887 Specimen Type 31208-2
511402 Maternal Cell Contamination 511888 Result 41103-3
511402 Maternal Cell Contamination 511889 Director Review 72486-4
511402 Maternal Cell Contamination 512123 PDF 80563-0

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