Vectra®

CPT: 81490
Updated on 11/25/2024
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Synonyms

  • Vectra® DA Disease Activity Test

Expected Turnaround Time

6 - 8 days



Specimen Requirements


Specimen

Serum


Volume

2 mL


Minimum Volume

1 mL


Container

Gel-barrier tube, red-top tube or serum transfer tube


Collection

Allow specimen to clot for 30 minutes. Centrifuge and separate from cells within 45 minutes of draw. Transfer to a plastic transport tube before shipping.


Storage Instructions

Ship on frozen cool packs or dry ice. Ship with enough dry ice so ice exists upon receipt of package. Samples cannot go above room temperature.


Stability Requirements

TemperaturePeriod
Room temperature3 days
Refrigerated14 days
Frozen326 days

Causes for Rejection

Gross hemolysis; gross lipemia; improper labeling; patients less than 18 years old or more than 100 years old


Test Details


Use

Vectra® DA measures the concentration of 12 serum proteins. An algorithm is applied to these concentrations to calculate a quantitate disease activity score ranging from 1 to 100. Test results are intended to aid in the assessment of disease activity in RA patients when used in conjunction with standard clinical assessment. This test is not intended or validated to diagnose RA.

An order for Vectra® DA includes and requires an order for 12 biomarkers: VCAM-1, EGF, VEGF-A, IL-6, TNF-RI, MMP-1, YKL-40, Leptin, Resistin, SAA, CRP. These 12 biomarkers are required to generate the Vectra® DA test score. By ordering Vectra® DA, you are ordering all 12 biomarkers and are acknowledging that Labcorp cannot provide a Vectra® DA test result without these 12 biomarkers. Vectra® DA was validated in adults with Rheumatoid Arthritis (RA).


Methodology

Multiplex bead-based immunoassay and Meso Scale Discovery Multi-array Platform


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