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Labcorp.com

Vectra®

CPT: 81490
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Synonyms

  • Vectra® DA Disease Activity Test

Expected Turnaround Time

6 - 8 days


Specimen Requirements


Specimen

Serum


Volume

2 mL


Minimum Volume

1 mL


Container

Gel-barrier tube, red-top tube or serum transfer tube


Collection

Allow specimen to clot for 30 minutes. Centrifuge and separate from cells within 45 minutes of draw. Transfer to a plastic transport tube before shipping.


Storage Instructions

Ship on frozen cool packs or dry ice. Ship with enough dry ice so ice exists upon receipt of package. Samples cannot go above room temperature.


Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

2 months


Causes for Rejection

Gross hemolysis; gross lipemia; improper labeling; patients less than 18 years old or more than 100 years old


Test Details


Use

Vectra® DA measures the concentration of 12 serum proteins. An algorithm is applied to these concentrations to calculate a quantitate disease activity score ranging from 1 to 100. Test results are intended to aid in the assessment of disease activity in RA patients when used in conjunction with standard clinical assessment. This test is not intended or validated to diagnose RA.

An order for Vectra® DA includes and requires an order for 12 biomarkers: VCAM-1, EGF, VEGF-A, IL-6, TNF-RI, MMP-1, YKL-40, Leptin, Resistin, SAA, CRP. These 12 biomarkers are required to generate the Vectra® DA test score. By ordering Vectra® DA, you are ordering all 12 biomarkers and are acknowledging that Labcorp cannot provide a Vectra® DA test result without these 12 biomarkers. Vectra® DA was validated in adults with Rheumatoid Arthritis (RA).


Methodology

Multiplex bead-based immunoassay and Meso Scale Discovery Multi-array Platform


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
504965 Vectra(R) 75635-3 504966 Vectra Score 75633-8
504965 Vectra(R) 75635-3 504967 Risk of Radiographic Progress % N/A
504965 Vectra(R) 75635-3 504969 Vectra(R) Level 75634-6
504965 Vectra(R) 75635-3 504968 Test Description N/A
504965 Vectra(R) 75635-3 504973 SAA Result ug/mL 1847-3
504965 Vectra(R) 75635-3 504974 CRP Result mg/L 1988-5
504965 Vectra(R) 75635-3 504975 VCAM-1 Result ug/mL 75627-0
504965 Vectra(R) 75635-3 504976 IL-6 Result pg/mL 26881-3
504965 Vectra(R) 75635-3 504977 TNF-RI Result ng/mL 75629-6
504965 Vectra(R) 75635-3 504978 EGF Result pg/mL 14049-1
504965 Vectra(R) 75635-3 504979 VEGF-A Result pg/mL 75628-8
504965 Vectra(R) 75635-3 504981 Leptin Result ng/mL 21365-2
504965 Vectra(R) 75635-3 504982 Resistin Result ng/mL 75632-0
504965 Vectra(R) 75635-3 504983 MMP-1 Result ng/mL 75630-4
504965 Vectra(R) 75635-3 504984 MMP3 Result ng/mL 75631-2
504965 Vectra(R) 75635-3 504985 YKL-40 Result ng/mL 48663-9
504965 Vectra(R) 75635-3 504999 Biomarker Comment: N/A
504965 Vectra(R) 75635-3 504986 Footnote/History N/A
504965 Vectra(R) 75635-3 504970 Clinical Validation N/A
504965 Vectra(R) 75635-3 504997 Vectra(R) PDF 51969-4

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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf