This assay which measures whole blood HCQ is the preferred assay for evaluation of lupus and other autoimmune patients on daily hydroxychloroquine.
This test should be ordered after 3 - 6 months of daily HCQ to assess daily dosage in lupus where drug action and efficacy are cumulative. In lupus, several weeks or months may be required to reach maximum therapeutic benefit that correlates with whole blood HCQ measurement.
7 - 10 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
For more information, please view the literature below.
Therapeutic Drug Monitoring Options for Rheumatoid Arthritis Flyer
0.4 mL (Note: This volume does not allow for repeat testing.)
Lavender-top (EDTA) tube
Collect whole blood into lavender-top (EDTA) tube. Refrigerate immediately.
This assay measures the whole blood concentration of hydroxychloroquine. Monitoring HCQ may improve adherence, and whole blood HCQ concentrations may be useful in titrating dose to achieve maximal clinical benefit in lupus while minimizing long-term retinal toxicity in lupus and other chronic autoimmune diseases.
In lupus, RA and other autoimmune diseases, several weeks or months may be required to reach maximum therapeutic benefit that correlates with whole blood HCQ measurement.
This test should be ordered after 3 - 6 months of daily HCQ to assess daily dosage in lupus, RA and other autoimmune diseases.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|504814||Hydroxychloroquine, WB||95921-3||504824||Hydroxychloroquine, WB||ng/mL||95921-3|
|Reflex Table for Hydroxychloroquine, WB|
|Order Code||Order Name||Result Code||Result Name||UofM||Result LOINC|
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