Test Details
Methodology
HLA results are obtained using Next Generation Sequencing (NGS).
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HLA results are obtained using Next Generation Sequencing (NGS). |
Result Turnaround Time
3 - 7 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
High resolution HLA typing is preferred for matching of bone marrow transplant donors and recipients. Other clinical indications may require high resolution typing to rule out alternative allele combinations.
High resolution typing for DRB1 will meet the following criteria: All ambiguities within exon 2, which defines the antigen recognition site, will be resolved. Those ambiguities that remain will be reported as an allele code.
Special Instructions
If you have questions, please call 800-533-1037 (HLA customer service) for assistance in selecting the proper HLA test for the patient.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
This test was developed |
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration. |
Specimen Requirements
Specimen
Whole blood or buccal swabs
Volume
7 mL whole blood or four buccal swabs
Minimum Volume
3 mL whole blood or four buccal swabs
Container
Lavender-top (EDTA) tube or four buccal swabs in a sealed envelope (buccal swab kit). When submitting buccal swabs, please use a buccal swab kit provided by LabCorp. To obtain the buccal swab kit, please telephone 800-533-1037.
Storage Instructions
Maintain specimen at room temperature; protect from extreme heat or cold. Do not freeze.
Causes for Rejection
Hemolyzed specimen; clotted specimen; wrong specimen container
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 176082 | HLA-DRB1 (HR) DRB345 (IR) | 166215 | DRB1 | 57298-2 | ||
| 176082 | HLA-DRB1 (HR) DRB345 (IR) | 166223 | DRB1 | 57298-2 | ||
| 176082 | HLA-DRB1 (HR) DRB345 (IR) | 166226 | DRB3 | 59022-4 | ||
| 176082 | HLA-DRB1 (HR) DRB345 (IR) | 166229 | DRB3 | 59022-4 | ||
| 176082 | HLA-DRB1 (HR) DRB345 (IR) | 166227 | DRB4 | 59021-6 | ||
| 176082 | HLA-DRB1 (HR) DRB345 (IR) | 166230 | DRB4 | 59021-6 | ||
| 176082 | HLA-DRB1 (HR) DRB345 (IR) | 166228 | DRB5 | 59020-8 | ||
| 176082 | HLA-DRB1 (HR) DRB345 (IR) | 166232 | DRB5 | 59020-8 | ||
| 176082 | HLA-DRB1 (HR) DRB345 (IR) | 167384 | HLA Methodology | 49549-9 | ||
| Order Code | 176082 | |||||
| Order Code Name | HLA-DRB1 (HR) DRB345 (IR) | |||||
| Order Loinc | ||||||
| Result Code | 166215 | |||||
| Result Code Name | DRB1 | |||||
| UofM | ||||||
| Result LOINC | 57298-2 | |||||
| Order Code | 176082 | |||||
| Order Code Name | HLA-DRB1 (HR) DRB345 (IR) | |||||
| Order Loinc | ||||||
| Result Code | 166223 | |||||
| Result Code Name | DRB1 | |||||
| UofM | ||||||
| Result LOINC | 57298-2 | |||||
| Order Code | 176082 | |||||
| Order Code Name | HLA-DRB1 (HR) DRB345 (IR) | |||||
| Order Loinc | ||||||
| Result Code | 166226 | |||||
| Result Code Name | DRB3 | |||||
| UofM | ||||||
| Result LOINC | 59022-4 | |||||
| Order Code | 176082 | |||||
| Order Code Name | HLA-DRB1 (HR) DRB345 (IR) | |||||
| Order Loinc | ||||||
| Result Code | 166229 | |||||
| Result Code Name | DRB3 | |||||
| UofM | ||||||
| Result LOINC | 59022-4 | |||||
| Order Code | 176082 | |||||
| Order Code Name | HLA-DRB1 (HR) DRB345 (IR) | |||||
| Order Loinc | ||||||
| Result Code | 166227 | |||||
| Result Code Name | DRB4 | |||||
| UofM | ||||||
| Result LOINC | 59021-6 | |||||
| Order Code | 176082 | |||||
| Order Code Name | HLA-DRB1 (HR) DRB345 (IR) | |||||
| Order Loinc | ||||||
| Result Code | 166230 | |||||
| Result Code Name | DRB4 | |||||
| UofM | ||||||
| Result LOINC | 59021-6 | |||||
| Order Code | 176082 | |||||
| Order Code Name | HLA-DRB1 (HR) DRB345 (IR) | |||||
| Order Loinc | ||||||
| Result Code | 166228 | |||||
| Result Code Name | DRB5 | |||||
| UofM | ||||||
| Result LOINC | 59020-8 | |||||
| Order Code | 176082 | |||||
| Order Code Name | HLA-DRB1 (HR) DRB345 (IR) | |||||
| Order Loinc | ||||||
| Result Code | 166232 | |||||
| Result Code Name | DRB5 | |||||
| UofM | ||||||
| Result LOINC | 59020-8 | |||||
| Order Code | 176082 | |||||
| Order Code Name | HLA-DRB1 (HR) DRB345 (IR) | |||||
| Order Loinc | ||||||
| Result Code | 167384 | |||||
| Result Code Name | HLA Methodology | |||||
| UofM | ||||||
| Result LOINC | 49549-9 |