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Parvovirus B19 (Human), IgG, IgM

CPT: 86747(x2)
Updated on 01/29/2020
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Synonyms

  • Human Parvovirus B19, IgG, IgM

Test Includes

Human parvovirus B19, IgG; human parvovirus B19, IgM

Human parvovirus B19, IgG; human parvovirus B19, IgM


Expected Turnaround Time

1 - 5 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.5 mL


Container

Red-top tube or gel-barrier tube


Storage Instructions

Maintain specimen at room temperature.


Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3


Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination


Test Details


Use

Differential diagnosis of acute or recent infection from past infection with human parvovirus associated with erythema infectiosum (fifth disease), aplastic crisis, and fetal infection


Methodology

Enzyme immunoassay (EIA)


Reference Interval

Negative: IgG: <0.9 index, IgM: <0.9 index


Additional Information

IgM antibodies are detectable two weeks after exposure. IgG antibody production usually occurs 18 to 24 days after exposure. The presence of IgM antibodies to parvovirus B19 provide definite evidence of recent infection.


References

Anderson MJ, Hall SM, Serjeant GR. Current Trends: Risks Associated With Human Parvovirus B19 Infection.MMWR. 1989 Feb 17; 38(6):81-88,93-97.
Griffin TC, Squires JE, Timmons CF, Buchanan GR. Chronic human parvovirus B19-induced erythroid hypoplasia as the initial manifestation of human immunodeficiency virus infection. J Pediatr. 1991 Jun; 118(6):899-901. 1645771
Schwarz TF, Modrow S, Hottentrager B, et al. New oligopeptide immunoglobulin G test for human parvovirus B19 antibodies. J Clin Microbiol. 1991 Mar; 29(3):431-435. 1645365
Schwarz TF, Nerlich A, Hottenträger B, et al. Parvovirus B19 infection of the fetus. Am J Clin Pathol. 1990 Jul; 96(1):121-125. 1648876

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
163303 Parvovirus B19, Human, IgG/IgM 163312 Parvovirus B19, IgG index 5273-8
163303 Parvovirus B19, Human, IgG/IgM 163330 Parvovirus B19, IgM index 5274-6

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