Lipid Panel With Apolipoprotein B (ApoB)

CPT: 80061; 82172
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Test Includes

Cholesterol, total; Apolipoprotein B (ApoB); high-density lipoprotein (HDL) cholesterol; low-density lipoprotein (LDL) cholesterol (calculation); non-high-density lipoprotein (non-HDL) cholesterol (calculation = total cholesterol minus HDLC); triglycerides

Expected Turnaround Time

1 - 3 days

Related Documents

Specimen Requirements


Serum or plasma


1 mL

Minimum Volume

0.5 mL (Note: This volume does not allow for repeat testing.)


Spun NMR LipoTube (preferred); serum from a plain red-top tube, plasma from a lavender-top (EDTA-no gel), or green-top (heparin-no gel) tube is acceptable.


Collect specimen in NMR LipoTube (black-and-yellow-top tube), which is the preferred container. Plain red-top, green-top (heparin-no gel), or lavender-top (EDTA-no gel) tubes are also acceptable. Serum or plasma drawn in gel-barrier collection tubes other than the NMR LipoTube should not be used.

The NMR LipoTube is the only acceptable gel-barrier tube. Gently invert tube 8 to 10 times to mix contents and allow specimen to clot for 30 minutes upright at room temperature prior to centrifugation (Plasma tubes should not clot). Centrifuge specimen within two hours of collection at 1800 to 2200xg for 10 to 15 minutes to separate serum/plasma from the red cells and to avoid red cell contamination during shipment.

Note: All specimens should be centrifuged by the client, prior to shipment to Labcorp, to ensure sample integrity. Immediately after centrifugation, pipette separated red-top serum or green-top/lavender-top plasma into a transport tube and label accordingly (serum, heparin plasma, EDTA plasma).

Storage Instructions


Stability Requirements



Room temperature

LipoTube Serum: 7 days; Plain Serum: 5 days; EDTA Plasma: 7 days; Sodium Heparin Plasma: 6 days


All tubes: 14 days


All tubes: 14 days (Note: Triglyceride values in frozen samples with high values >400 mg/dL may be decreased more than 10% when frozen.)

Freeze/thaw cycles

ApoB serum tubes: Stable x4; NMR LipoTubes: Stable x1; All other tubes: Stable x5

Patient Preparation

Patient fasting is not required; however, in conditions where triglyceride values provide a priori diagnostic information, such as screening for familial hypercholesterolemia or early onset heart disease, pancreatitis, or confirming hypertriglyceridemia, the patient should be counseled to fast 12 to 14 hours prior to blood draw.

Causes for Rejection

Unspun specimens; plasma/serum contaminated with red cells; citrated plasma (light blue-top tube); gross hemolysis; specimen received in gel-barrier collection tube other than the LipoTube

Test Details


This "Extended Lipid Panel" quantifies the components of a typical lipid panel (TC, HDL-C and TG) along with ApoB by nuclear magnetic resonance (NMR) spectroscopy using the Vantera NMR Clinical Analyzer. Results from the Extended Lipid Panel Assay can be used by physicians to assist in CVD risk assessment. The principal protein component of LDL particles, ApoB, has been shown to be associated with CVD and is also an important CVD risk factor.


If triglyceride level is >800 mg/dL, LDL cholesterol will not be calculated.


Nuclear magnetic resonance (NMR)


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
123544 Lipid Panel+ApoB 123477 Cholesterol, Total mg/dL 2093-3
123544 Lipid Panel+ApoB 123476 Triglycerides mg/dL 2571-8
123544 Lipid Panel+ApoB 123475 HDL-C mg/dL 2085-9
123544 Lipid Panel+ApoB 123478 Non-HDL Cholesterol mg/dL 43396-1
123544 Lipid Panel+ApoB 123479 LDL-C (NIH Calc) mg/dL 13457-7
123544 Lipid Panel+ApoB 123491 Apolipoprotein B mg/dL 1884-6

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