Serum protein electrophoresis with relative percentages and quantitation of albumin; α1-, α2-, β-, and γ-globulin fractions; graph of fractions; quantitation of total protein and M-spike if present; quantitation of serum free κ and λ light chains plus κ:λ ratio
3 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
For more information, please view the literature below.
Red-top tube or gel-barrier tube
Sample should be allowed to clot and the serum separated as soon as possible to prevent hemolysis.
PE: Stable when covered at room temperature 25°C for four days; stable refrigerated at 2°C to 8°C for two weeks; stable frozen at -20°C for six months.
FLC: Refrigerate; samples are stable for 21 days at 2°C to 8°C. For longer storage, freeze at -20°C.
Lipemia; hemolysis; plasma specimen
Detect and identify monoclonal immunoglobulin gammopathies
Protein electrophoresis: agarose media; free κ and λ light chains: turbidimetric quantitation
Elevated serum levels of monoclonal FLC are associated with malignant plasma cell proliferation (eg, multiple myeloma), primary amyloidosis, and light chain deposition disease. Raised serum levels of polyclonal FLC may be associated with autoimmune diseases such as systemic lupus erythematosus.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|121210||PE and FLC, Serum||001073||Protein, Total||g/dL||2885-2|
|121210||PE and FLC, Serum||001488||Albumin||g/dL||2862-1|
|121210||PE and FLC, Serum||001489||Alpha-1-Globulin||g/dL||2865-4|
|121210||PE and FLC, Serum||001490||Alpha-2-Globulin||g/dL||2868-8|
|121210||PE and FLC, Serum||001491||Beta Globulin||g/dL||2871-2|
|121210||PE and FLC, Serum||001492||Gamma Globulin||g/dL||2874-6|
|121210||PE and FLC, Serum||001493||M-Spike||g/dL||33358-3|
|121210||PE and FLC, Serum||011052||Globulin, Total||g/dL||10834-0|
|121210||PE and FLC, Serum||011149||A/G Ratio||1759-0|
|121210||PE and FLC, Serum||011150||Please note:||77202-0|
|121210||PE and FLC, Serum||001498||11502-2|
|121210||PE and FLC, Serum||121138||Free Kappa Lt Chains,S||mg/L||36916-5|
|121210||PE and FLC, Serum||121139||Free Lambda Lt Chains,S||mg/L||33944-0|
|121210||PE and FLC, Serum||121141||Kappa/Lambda Ratio,S||48378-4|
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