Find Locations
For hours, walk-ins and appointments.Expected Turnaround Time
Within 1 day
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Serum (preferred) or plasma
Volume
1 mL
Minimum Volume
0.2 mL (Note: This volume does not allow for repeat testing.)
Container
Gel-barrier tube, transport tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection
Separate serum or plasma from cells within 45 minutes of collection.
Storage Instructions
Maintain specimen at room temperature.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 7 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x2 |
Causes for Rejection
Gross hemolysis; improper labeling; gross lipemia
Test Details
Use
Evaluate diabetic control, reflecting diabetic control over a shorter time period (one to three weeks) than that represented by hemoglobin A1c (four to eight weeks). Indicated as an index of longer-term control than glucose levels, especially in diabetic subjects with abnormal hemoglobins and in type 1 diabetes in children.1
Methodology
Colorimetric
Additional Information
Fructosamine is found in the plasma of both normal and diabetic individuals. “Fructosamine” is the term used to describe proteins that have been glycated (ie, are derivatives of the nonenzymatic reaction product of glucose and albumin). It has been advocated as an alternative test to hemoglobin A1c for the monitoring of long-term diabetic control. Fructosamine and hemoglobin A1c do not measure exactly the same thing, since fructosamine has a shorter half-life and appears to be more sensitive to short-term variations in glucose levels; however, this is not necessarily a disadvantage. Fructosamine is clearly superior in patients with abnormal hemoglobins because of the interference of abnormal hemoglobins in the anion-exchange chromatography methods for Hb A1c. Published reference interval for apparently healthy subjects between age 20 and 60 is 205−285 μmol/L and in a poorly-controlled diabetic population is 228−563 μmol/L with a mean of 396 μmol/L.
Footnotes
1. Cefalu WT, Mejia E, Puente GR, Fleishhacker D, Macaulay K. Correlation of serum fructosamine activity in type I diabetic children. Am J Med Sci. 1989 Apr; 297(4):244-246. 2705464
References
Croxson SC, Absalom S, Burden AC. Fructosamine in diabetes screening of the elderly. Ann Clin Biochem. 1991 May; 28(Pt 3):279-282. 1872575
Melzi d'Eril GV, Bosoni T, Solerte SB, Fioravanti M, Ferrari E. Performance and clinical significance of the new fructosamine assay in diabetic patients. Wien Klin Wochenschr Suppl. 1990; 180:60-63. 2321395
Narayanan S. Laboratory monitoring of gestational diabetes. Ann Clin Lab Sci. 1991 Nov-Dec; 21(6):392-401. 1781664
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 100800 | Fructosamine | 15069-8 | 100808 | Fructosamine | umol/L | 15069-8 |
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