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Epstein-Barr Virus (EBV) (Viral Capsid Antigen [VCA] and Early Antigen-Diffuse [EA(D)]), IgG Antibody Profile

Epstein-Barr Virus (EBV) (Viral Capsid Antigen [VCA] and Early Antigen [EA]), IgG Antibody Profile
Epstein-Barr Virus (EBV) (Viral Capsid Antigen [VCA] and Early Antigen-Diffuse [EA(D)]), IgG Antibody Profile
CPT: 86663; 86665
Updated on 12/15/2019
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Synonyms

  • EA(D)
  • EBV-EA
  • EBV-VCA
  • EBV-VCA/EA Antibodies, IgG
  • EBV-EA
  • EBV-VCA
  • EBV-VCA/EA Antibodies, IgG
  • EBV-EA
  • EBV-VCA
  • EBV-VCA/EA Antibodies, IgG
  • EA(D)
  • EBV-EA
  • EBV-VCA
  • EBV-VCA/EA Antibodies, IgG

Test Includes

Epstein-Barr virus (EBV) early antigen antibody, IgG; Epstein-Barr virus (EBV) antibody to viral capsid antigen, IgG


Expected Turnaround Time

1 - 2 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

2 mL


Container

Red-top tube or gel-barrier tube


Storage Instructions

Room temperature

Refrigerate. Specimen is stable for two days at room temperature or refrigerated. For storage longer than two days, freeze the specimen.

Room temperature


Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x4

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x4


Causes for Rejection

Hemolysis; lipemia; grossly icteric; visible particulate matter; gross bacterial contamination


Test Details


Use

Aid in the diagnosis of acute EBV (infectious mononucleosis) and EBV reactivation in conjunction with other serologic tests. The appearance of IgG antibodies to EA(D) is generally associated with the primary (acute) stage of EBV infection. For most individuals, EA(D) IgG antibodies are transient and are ogten undetectable after 6 months while VCA IgG antibodies persist indefinitely.

Aid in the diagnosis of acute EBV (infectious mononucleosis) and EBV reactivation in conjunction with other serologic tests. The appearance of IgG antibodies to EA(D) is generally associated with the primary (acute) stage of EBV infection. For most individuals, EA(D) IgG antibodies are transient and are ogten undetectable after 6 months while VCA IgG antibodies persist indefinitely.


Limitations

The results for this test are not by themselves diagnostic and should be considered in association with other clinical data and patient symptoms.

This test is intended for qualitative determination only. The numeric value of the final result above the cutoff is not indicative of the amount of EBV-EA or EBV-VCA antibodies.


Methodology

Chemiluminescent immunoassay (CLIA)


Reference Interval

See individual tests.


Additional Information

Set up and reported Monday thru Friday.


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
096255 EBV VCA/EA Ab, IgG 096252 EBV Early Antigen Ab, IgG U/mL 24007-7
096255 EBV VCA/EA Ab, IgG 096235 EBV Ab VCA, IgG U/mL 5157-3

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