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Varicella Zoster Virus (VZV) Antibodies, IgG

CPT: 86787
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Synonyms

  • Chickenpox Titers
  • Herpes Zoster Antibodies
  • VZV IgG

Expected Turnaround Time

1 - 2 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

0.5 mL


Minimum Volume

0.2 mL


Container

Red-top tube or gel-barrier tube


Storage Instructions

Room temperature


Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x4


Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination


Test Details


Use

Diagnose VZV infection; determine adult susceptibility to infection


Methodology

Chemiluminescent immunoassay (CLIA)


Reference Interval

• Negative: <135 index

• Equivocal: 135−165 index

• Positive: >165 index


Additional Information

Although most cases of varicella or zoster are clinically unambiguous, serology may be occasionally useful in the differential diagnosis of other blistering illnesses or when infection shows an unusual complication, such as hepatitis. It may also be important to establish whether an individual is susceptible when clinical history is unclear, or when varicella immune globulin may be needed, as in the immunocompromised host or cancer patient on toxic chemotherapy. Zoster is more common with aging and may occur in the face of significant antibody titers, demonstrating that cell-mediated immunity is also significant.


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
096206 Varicella-Zoster V Ab, IgG 5403-1 096210 Varicella Zoster IgG index 5403-1

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