Isohemagglutinin Titer

CPT: 86940
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Synonyms

  • Anti-A Titer
  • Anti-B Titer
  • Isoagglutinins

Test Includes

Blood grouping; anti-A titer; anti-B titer; antibody screen


Expected Turnaround Time

3 - 5 days


Related Documents


Specimen Requirements


Specimen

Whole blood


Volume

4 mL


Minimum Volume

3 mL


Container

Lavender-top (EDTA) tube


Storage Instructions

Refrigerate.


Causes for Rejection

Gross hemolysis; bacterial or other contamination


Test Details


Use

Determine the titer of isohemagglutinins (anti-A and/or anti-B) in serum; the absence of expected isohemagglutinins may suggest an immunological deficiency. This test is not recommended for the determination of immunodeficiency. Dependent upon a variety of factors, normal titers are >1:8.


Limitations

The presence of cold agglutinins other than anti-A and anti-B may interfere with test interpretation. Newborns, infants younger than six months of age, and patients who have undergone immunosuppressive therapy may not demonstrate expected ABO isohemagglutinins.


Methodology

Hemagglutination


References

Issitt PD, Anstee DJ. Applied Blood Group Serology. 4th ed. 1998.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
096164 Isohemagglutinin Titer 18274-1 016428 Antibody Screen 18274-1
096164 Isohemagglutinin Titer 18274-1 016445 Blood Grouping 883-9
096164 Isohemagglutinin Titer 18274-1 016436 A Titer 30314-9
096164 Isohemagglutinin Titer 18274-1 016444 B Titer 30201-8

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