Isohemagglutinin Titer

CPT: 86940
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  • Anti-A Titer
  • Anti-B Titer
  • Isoagglutinins

Test Includes

Blood grouping; anti-A titer; anti-B titer; antibody screen

Expected Turnaround Time

3 - 5 days

Related Documents

Specimen Requirements


Whole blood


4 mL

Minimum Volume

3 mL


Lavender-top (EDTA) tube

Storage Instructions


Causes for Rejection

Gross hemolysis; bacterial or other contamination

Test Details


Determine the titer of isohemagglutinins (anti-A and/or anti-B) in serum; the absence of expected isohemagglutinins may suggest an immunological deficiency. This test is not recommended for the determination of immunodeficiency. Dependent upon a variety of factors, normal titers are >1:8.


The presence of cold agglutinins other than anti-A and anti-B may interfere with test interpretation. Newborns, infants younger than six months of age, and patients who have undergone immunosuppressive therapy may not demonstrate expected ABO isohemagglutinins.




Issitt PD, Anstee DJ. Applied Blood Group Serology. 4th ed. 1998.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
096164 Isohemagglutinin Titer 18274-1 016428 Antibody Screen 18274-1
096164 Isohemagglutinin Titer 18274-1 016445 Blood Grouping 883-9
096164 Isohemagglutinin Titer 18274-1 016436 A Titer 30314-9
096164 Isohemagglutinin Titer 18274-1 016444 B Titer 30201-8

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