Test Details
Methodology
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Result Turnaround Time
3 - 6 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
This test is used for therapeutic drug management.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen Requirements
Specimen
Serum or plasma
Volume
3 mL
Minimum Volume
0.5 mL
Container
Red-top (no additive) tube or green-top (heparin) tube; gel-barrier tubes are not recommended
Collection Instructions
Transfer separated serum or plasma to a plastic transport tube. Trough levels are most reproducible.
Stability Requirements
| Temperature | Period |
|---|---|
| Room temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Reference Range
Buprenorphine: 1.00–10.00 ng/mL; norbuprenorphine: not established
Storage Instructions
Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 070103 | BUPRENORPHINE AND MTB, SP | 75368-1 | 070101 | BUPRENORPHINE | ng/mL | 75368-1 |
| 070103 | BUPRENORPHINE AND MTB, SP | 75368-1 | 070102 | NORBUPRENORPHINE | ng/mL | 75370-7 |
| Order Code | 070103 | |||||
| Order Code Name | BUPRENORPHINE AND MTB, SP | |||||
| Order Loinc | 75368-1 | |||||
| Result Code | 070101 | |||||
| Result Code Name | BUPRENORPHINE | |||||
| UofM | ng/mL | |||||
| Result LOINC | 75368-1 | |||||
| Order Code | 070103 | |||||
| Order Code Name | BUPRENORPHINE AND MTB, SP | |||||
| Order Loinc | 75368-1 | |||||
| Result Code | 070102 | |||||
| Result Code Name | NORBUPRENORPHINE | |||||
| UofM | ng/mL | |||||
| Result LOINC | 75370-7 |