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α-Fetoprotein, serum; dimeric inhibin A (DIA); human chorionic gonadotropin (hCG); unconjugated estriol (uE3)
The following information must be provided: gestational age, date on which the patient was the stated gestational age, how gestational age was determined (LMP, EDD, US), patient's weight, patient's date of birth, patient's race (white, black, other), and insulin-dependent diabetic status. Also indicate relevant patient history (eg, prior neural tube defects, Down syndrome, ultrasound anomalies, or previous maternal serum screening specimen during this pregnancy). Complete information is necessary to interpret the test. Patient information may be provided to the laboratory using The Maternal Prenatal Screening requisition form 0900. Specimens must be collected before amniocentesis.
Down syndrome screening is offered for gestational ages 15.0 to 21.9 weeks. Open spina bifida screening is offered for gestational ages 15.0 to 23.9 weeks. The optimal gestational age for open spina bifida screening is 16.0 to 18.9 weeks.
2 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
3 mL (Note: This volume does not allow for repeat testing.)
Collect in serum separator tube with gel barrier. Allow blood to clot, avoiding hemolysis. Separate serum from cells by centrifugation. Transport spun tube to testing laboratory.
Pour-off is not advised. Maternal serum specimens must be drawn prior to amniocentesis to avoid contamination with fetal blood.
Gross hemolysis; gross lipemia; quantity not sufficient for analysis; improper specimen type
Screening test for open neural tube defects (detects 80% open spina bifida, 90% anencephaly), Down syndrome (detects 75% to 80%), and trisomy 18 (detects 73%)
AFP tetra is a screening test. A positive AFP tetra result means that more diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect or chromosome abnormality is present.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|017319||AFP Tetra||017320||Test Results:||49092-0|
|017319||AFP Tetra||017368||Gest. Age on Collection Date||WEEKS||18185-9|
|017319||AFP Tetra||017369||Gestat. Age Based On||21299-3|
|017319||AFP Tetra||017370||Maternal Age At EDD||yr||43993-5|
|017319||AFP Tetra||017373||Insulin Dep Diabetes||44877-9|
|017319||AFP Tetra||017374||Multiple Gestation||45371-2|
|017319||AFP Tetra||017375||AFP Value||ng/mL||1834-1|
|017319||AFP Tetra||017376||AFP MoM||23811-3|
|017319||AFP Tetra||017377||hCG Value||mIU/mL||19080-1|
|017319||AFP Tetra||017378||hCG MoM||32166-1|
|017319||AFP Tetra||017379||uE3 Value||ng/mL||2250-9|
|017319||AFP Tetra||017380||uE3 MoM||21264-7|
|017319||AFP Tetra||017381||DIA Value||pg/mL||23883-2|
|017319||AFP Tetra||017382||DIA MoM||36904-1|
|017319||AFP Tetra||017383||OSBR Risk 1 IN||48803-1|
|017319||AFP Tetra||017384||DSR (Second Trimester) 1 IN||43995-0|
|017319||AFP Tetra||017385||DSR (By Age) 1 IN||49090-4|
|017319||AFP Tetra||017392||T18 Risk||43994-3|
|017319||AFP Tetra||017391||T18 (By Age)||47223-3|
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