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Complement C1q, Quantitative

CPT: 86160
Updated on 12/9/2019
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Special Instructions

State patient's sex on the request form.


Expected Turnaround Time

7 - 9 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.1 mL (Note: This volume does not allow for repeat testing.)


Container

Red-top tube or gel-barrier tube


Collection

Separate serum from cells.


Storage Instructions

Room temperature


Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3


Causes for Rejection

Chylous serum; gross bacterial contamination. Plasma should be avoided since fibrin may result in the appearance of nonspecific precipitation, which may adversely affect interpretation.


Test Details


Use

Evaluate the classical complement pathway


Methodology

Radial immunodiffusion (RID)


Reference Interval

See table.

Age

Male (mg/dL)

Female (mg/dL)

0 to 1 y

Not established

Not established

2 to 5 y

9.8-18.5

9.7-19.1

6 to 17 y

10.2-19.6

10.2-19.4

>17 y

10.2-20.3

10.3-20.5

Male: 11.8−23.8 mg/dL; female: 11.8−24.4 mg/dL

See table.

Age

Male (mg/dL)

Female (mg/dL)

0 to 1 y

Not established

Not established

2 to 5 y

9.8-18.5

9.7-19.1

6 to 17 y

10.2-19.6

10.2-19.4

>17 y

10.2-20.3

10.3-20.5


Additional Information

Levels are depressed in various immunodeficiency states including x-linked hypogammaglobulinemia and severe combined immunodeficiency (10% to 25% of normal levels). Genetic deficiencies of C1q have been described.


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
016824 Complement C1q, Quantitative 4478-4 016824 Complement C1q, Quantitative mg/dL 4478-4

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