Melanocyte-stimulating Hormone (MSH)

CPT: 83519
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  • Alpha-Melanocyte-stimulating Hormone

Special Instructions

Contact LabCorp supply department for collection kit.

Expected Turnaround Time

3 - 8 days

Related Documents

Specimen Requirements


Plasma with Trasylol®, frozen


2 mL

Minimum Volume

0.3 mL


Lavender-top (EDTA) tube


Trasylol® kits may be ordered through the PeopleSoft system (LabCorp N° 33328). Using a chilled 6-mL lavender-top (EDTA) tube taken from the kit, collect a whole blood specimen. Mix the specimen several times by inverting the EDTA collection tube. After removing the cap from the EDTA draw tube, take one of the sterile, Beral pipettes (from under the gray foam), and add 0.25 mL Trasylol® to the EDTA tube. Recap the EDTA tube and invert several times to mix well. Centrifuge the EDTA tube to separate the plasma from the cells, and immediately transfer the plasma into one of the brown screw-cap transfer tubes provided in the kit. There should be a "Trasylol® Added" label affixed to the brown transfer tubes. Cap and freeze the labeled transfer tube containing the EDTA plasma with Trasylol® added. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions


Stability Requirements



Room temperature



1 day


14 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Sample not collected with Trasylol®; sample not submitted in tube with Trasylol label; gross hemolysis; recently administered radioisotopes; specimen not received frozen; serum, sodium citrate, or heparinized plasma specimen; lipemia

Test Details


Results for this test are for research purposes only by the assay's manufacturer. The performance characteristics of this product have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.


Radioimmunoassay (RIA)

Reference Interval

0−40 pg/mL


Catania A, Airaghi L, Garofalo L, et al. The neuropeptide alpha-MSH in HIV infection and other disorders in humans. Ann N Y Acad Sci. 1998; 840:848-856. 9629310
Clark D, Thody AJ, Shuster S, et al. Immunoreactive α-MSH in human plasma in pregnancy. Nature. 1978; 273(5658):163-164. 643080
Krieger DT, Liotta AS, Brownstein MJ, et al. ACH, beta-lipotropin and related peptides in brain, pituitary, and blood. Recent Prog Horm Res. 1980; 36:277-344. 6251518
Reid RI, Lina N, Yen SS. Alpha-melanocyte stimulating hormone induces gonadotropin release. J Clin Endocrinol Metab. 1981; 52(1):159-161.6778891


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
010421 Melanocyte Stimulating Hormone 1820-0 010421 Melanocyte Stimulating Hormone pg/mL 1820-0

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