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Melanocyte-stimulating Hormone (MSH)

CPT: 83519
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Synonyms

  • Alpha-Melanocyte-stimulating Hormone

Special Instructions

Contact LabCorp supply department for collection kit.


Expected Turnaround Time

6 - 8 days


Related Documents


Specimen Requirements


Specimen

Plasma with Trasylol®, frozen


Volume

2 mL


Minimum Volume

0.3 mL


Container

Lavender-top (EDTA) tube


Collection

Trasylol® kits may be ordered through the PeopleSoft system (LabCorp N° 33328). Using a chilled 6-mL lavender-top (EDTA) tube taken from the kit, collect a whole blood specimen. Mix the specimen several times by inverting the EDTA collection tube. After removing the cap from the EDTA draw tube, take one of the sterile, Beral pipettes (from under the gray foam), and add 0.25 mL Trasylol® to the EDTA tube. Recap the EDTA tube and invert several times to mix well. Centrifuge the EDTA tube to separate the plasma from the cells, and immediately transfer the plasma into one of the brown screw-cap transfer tubes provided in the kit. There should be a "Trasylol® Added" label affixed to the brown transfer tubes. Cap and freeze the labeled transfer tube containing the EDTA plasma with Trasylol® added. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.


Storage Instructions

Freeze.


Stability Requirements

Temperature

Period

Room temperature

Unstable

Refrigerated

1 day

Frozen

14 days

Freeze/thaw cycles

Stable x1


Causes for Rejection

Sample not collected with Trasylol®; sample not submitted in tube with Trasylol label; gross hemolysis; recently administered radioisotopes; specimen not received frozen; serum, sodium citrate, or heparinized plasma specimen; lipemia


Test Details


Limitations

Results for this test are for research purposes only by the assay's manufacturer. The performance characteristics of this product have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.


Methodology

Radioimmunoassay (RIA)


Reference Interval

0−40 pg/mL


References

Catania A, Airaghi L, Garofalo L, et al. The neuropeptide alpha-MSH in HIV infection and other disorders in humans. Ann N Y Acad Sci. 1998; 840:848-856. 9629310
Clark D, Thody AJ, Shuster S, et al. Immunoreactive α-MSH in human plasma in pregnancy. Nature. 1978; 273(5658):163-164. 643080
Krieger DT, Liotta AS, Brownstein MJ, et al. ACH, beta-lipotropin and related peptides in brain, pituitary, and blood. Recent Prog Horm Res. 1980; 36:277-344. 6251518
Reid RI, Lina N, Yen SS. Alpha-melanocyte stimulating hormone induces gonadotropin release. J Clin Endocrinol Metab. 1981; 52(1):159-161.6778891

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
010421 Melanocyte Stimulating Hormone 1820-0 010421 Melanocyte Stimulating Hormone pg/mL 1820-0

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