Test Details
Methodology
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Result Turnaround Time
2 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Evaluate toxicity; monitor therapeutic levels
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Custom Additional Information
The drug is used in the treatment of general anxiety disorder, the management of ethanol withdrawal, and as an adjunct anticonvulsant drug. Half-life of elimination: 40 to 50 hours. Time to peak serum: approximately one hour.
Specimen Requirements
Specimen
Serum or plasma
Volume
1 mL
Minimum Volume
0.4 mL
Container
Red-top tube, lavender-top (EDTA) tube, or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.
Collection Instructions
Transfer separated serum or plasma to a plastic transport tube. Specimen should be collected prior to next dose unless otherwise noted.
Reference Range
Therapeutic: 0.5−2.0 μg/mL (reported as nordiazepam)
Storage Instructions
Refrigerate.
Causes for Rejection
Gel-barrier tube
References
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 007930 | Clorazepate (Tranxene(R)), S | 3498-3 | 007930 | Clorazepate (Tranxene(R)), S | ug/mL | 3498-3 |
| Order Code | 007930 | |||||
| Order Code Name | Clorazepate (Tranxene(R)), S | |||||
| Order Loinc | 3498-3 | |||||
| Result Code | 007930 | |||||
| Result Code Name | Clorazepate (Tranxene(R)), S | |||||
| UofM | ug/mL | |||||
| Result LOINC | 3498-3 |