Nonpregnant patients only.
4 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Serum from a serum separator tube
0.4 mL (Note: This volume does not allow for repeat testing.)
Gel-barrier serum separator tube; red top tubes (without gel barrier) should not be used
Sample collected with any tube other than a gel barrier (serum separator) tube
Evaluate postmenopausal vaginal bleeding due to peripheral conversion of androgenic steroids. Increased estrone levels may be associated with increased levels of circulating androgens and their subsequent peripheral conversion.
Enzyme immunoassay (EIA)
Tanner Stage I
Tanner Stage II
Tanner Stage III
Tanner Stage IV
Tanner Stage V
Adult (Premenopausal): 27−231
Menstrual Cycle (1-10 days): 19−149
Menstrual Cycle (11-20 days): 32−176
Menstrual Cycle (21-30 days): 37−200
Adult (Postmenopausal): 0−125
Estrone (E1) is a steroid, a weak estrogen, and a minor female sex hormone.3,4 Estrone is one of three major endogenous estrogens, the others being estradiol and estriol.3,4 Like the other estrogens, estrone is synthesized from cholesterol and secreted mainly from the gonads, though they can also be formed from adrenal androgens in adipose tissue. Estrone is primarily derived from metabolism of androstenedione in peripheral tissues, especially adipose tissues. Individuals with obesity have increased conversion of androstenedione to estrone, leading to higher concentrations. Estrone can be converted into estradiol and serves mainly as a precursor or metabolic intermediate of estradiol. In addition, an increase in the ratio of estrone to estradiol may be useful in assessing menopause in women.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|004564||Estrone, Serum||2258-2||004564||Estrone, Serum||pg/mL||2258-2|
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