Creatinine, 24-Hour Urine

CPT: 82570
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  • Urine Creatinine, 24-Hour

Test Includes

Urine creatinine in mg/dL and mg/24 hours

Special Instructions

Record total 24-hour urine volume on the request form.

Expected Turnaround Time

Within 1 day

Related Information

Related Documents

Specimen Requirements


Urine (24-hour)


10 mL aliquot of entire collection

Minimum Volume

0.5 mL aliquot (Note: This volume does not allow for repeat testing.)


Plastic urine container, with or without 6N HCl


If the specimen is a 24-hour collection instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely. Transport the specimen promptly to the laboratory. Container must be labeled with patient's full name, date and time collection started, and date and time collection finished.

Storage Instructions

Room temperature

Stability Requirements



Room temperature

7 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Times not indicated; improper labeling

Test Details


Renal function test when used as part of creatinine clearance; crude marker for completeness of 24-hour urine collections when collected for other purposes


Complete urine collections require vigilance on the part of nursing personnel. Ingestion of meat may increase creatinine values of urine collections as well as serum creatinine values. Drugs interfering with tubular creatinine secretion include cimetidine, trimethoprim, and probenecid. Creatinine reabsorption occurs with very low urine flow rates. Entities in which reabsorption occurs include severe congestive heart failure, uncontrolled diabetes mellitus, and acute renal failure.1



Additional Information

Urine creatinine is not ordered alone. Creatinine clearance, which requires a serum creatinine, offers useful renal function data. Serum creatinine alone is not an adequate index of glomerular filtration rate.1


1. Levey AS, Perrone RD, Madias NE. Serum creatinine and renal function. Annu Rev Med. 1988; 39:465-490 (review). 3285786


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
003012 Creatinine, 24-Hour Urine 2162-6 013672 Creatinine, Urine mg/dL 2161-8
003012 Creatinine, 24-Hour Urine 2162-6 013227 Creatinine, Ur 24hr mg/24 hr 2162-6

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